Multicomponent reactions as a potent tool for the synthesis of benzodiazepines

H Farhid, V Khodkari, MT Nazeri… - Organic & …, 2021 - pubs.rsc.org
Benzodiazepines (BZDs), a diverse class of benzofused seven-membered N-heterocycles,
display essential pharmacological properties and play vital roles in some biochemical …

Ultrasound-assisted transition-metal-free catalysis: a sustainable route towards the synthesis of bioactive heterocycles

B Borah, LR Chowhan - RSC advances, 2022 - pubs.rsc.org
Heterocycles of synthetic and natural origin are a well-established class of compounds
representing a broad range of organic molecules that constitute over 60% of drugs and …

Synthesis of imidazole-based molecules under ultrasonic irradiation approaches

XL Yu, YH Fan, XN Zheng, JF Gao, LG Zhuang, YL Yu… - Molecules, 2023 - mdpi.com
Imidazole-based compounds are a series of heterocyclic compounds that exhibit a wide
range of biological and pharmaceutical activities. However, those extant syntheses using …

Synthesis of α-keto aldehydes via selective Cu (i)-catalyzed oxidation of α-hydroxy ketones

S Zheng, W Smit, A Spannenberg, S Tin… - Chemical …, 2022 - pubs.rsc.org
An efficient approach to synthesize α-keto aldehydes was established through selective
oxidation of α-hydroxy ketones catalyzed by Cu (I) using oxygen as oxidant. A wide array of …

Recent advances in meglumine catalyzed organic synthesis: A comprehensive review

DR Bhandari, UJ Khengar, RH Vekariya… - Synthetic …, 2024 - Taylor & Francis
Meglumine, an amino sugar alcohol compound, has recently emerged as a promising
catalyst in various organic transformations due to its unique properties. This review provides …

A redox active organodiselenide as an efficacious catalyst for the synthesis of oxygen-containing heterocyclic compounds

N Rahman, N Kushwah, KI Priyadarsini - New Journal of Chemistry, 2023 - pubs.rsc.org
3, 3′-Diselenodipropionic acid (DSePA) is a water-soluble deaminated analogue of
selenocystine. Owing to its acidic groups and the redox activity of the diselenide moiety …

Synthesis of 2-aryl quinoxaline derivatives and their in silico investigation for breast cancer medication

BD Wadhwani, D Mali, L Kumar Agarwal… - Synthetic …, 2024 - Taylor & Francis
The main objective of the present work is to synthesize and identify the potential breast
cancer medication of 2-aryl quinoxaline derivatives via in silico investigations. Synthesis of 2 …

A convenient one-pot synthesis of novel heterocyclic systems of 9-chloro-4-methyl-6,11-dihydro-5H-benzo[b]pyrimido[4,5-e][1,4]diazepine and inhibitory evaluation …

F Assadzadeh, T Afrough, H Eshghi… - Journal of the Iranian …, 2023 - Springer
A convenient one-pot two-step strategy for synthesis of the novel tricyclic system 9-chloro-4-
methyl-6, 11-dihydro-5 H-benzo [b] pyrimido [4, 5-e][1, 4] diazepine have been synthesized …

β-cyclodextrin: Green catalyst for the efficient and expeditious synthesis of benzodiazepines under aqueous conditions

LB Masram, SS Salim, YU Gadkari… - Synthetic …, 2022 - Taylor & Francis
An efficient and facile green method for synthesis of four substituted 1, 5-benzodiazepine
derivatives via a three-component reaction of dimedone, o-phenyl diamine, and various …

Water Extract of Onion Catalyst: A Sustainable Approach for the Synthesis of 4-Substituted 1, 5-Benzodiazepine Derivatives via an In Situ Generated Enaminones

L Selvaraj, R Eswaran, VK Natesan… - Current …, 2024 - ingentaconnect.com
Background: A simple, convenient and environmentally benign green protocol has been
developed for the one-pot synthesis of 4-substituted-1, 5-benzodiazepines through three …