Liposomes are essentially a subtype of nanoparticles comprising a hydrophobic tail and a
hydrophilic head constituting a phospholipid membrane. The spherical or multilayered …

Cryogenic transmission electron microscopy (cryo-TEM) has evolved into an indispensable
tool for the characterization of colloidal drug delivery systems. It can be applied to study the …

An understanding of the factors that affect liposome size, drug loading, stability and drug
release is critical for the rational design of liposomes with desired pharmacokinetics and …

Introduction: The use of liposomes increases the therapeutic index of many drugs, and also
offers drug targeting and controlled release. The commercial impact of liposomes is …

Lipid-based complex injectables are renowned for their effectiveness in delivering drugs,
with many approved products. While significant strides have been made in formulating …

The presence of poly (ethylene glycol)(PEG) at the surface of a liposomal carrier has been
clearly shown to extend the circulation lifetime of the vehicle. To this point, the extended …

The incorporation of poly (ethylene glycol)(PEG)-conjugated lipids in lipid-based carriers
substantially prolongs the circulation lifetime of liposomes. However, the mechanism (s) by …

Liposomes represent a widely varied and malleable class of drug carriers generally
characterized by the presence of one or more amphiphile bilayers enclosing an interior …

Liposomes have been attracted considerable attention as phospholipid spherical vesicles,
over the past 40 years. These lipid vesicles are valued in biomedical application due to their …

Introduction Many small molecules and biologic therapeutics have been developed for solid
tumor therapy. However, the unique physiology of tumors makes the actual delivery of these …