[HTML][HTML] ATRX promotes heterochromatin formation to protect cells from G-quadruplex DNA-mediated stress

YC Teng, A Sundaresan, R O'Hara, VU Gant… - Nature …, 2021 - nature.com
ATRX is a tumor suppressor that has been associated with protection from DNA replication
stress, purportedly through resolution of difficult-to-replicate G-quadruplex (G4) DNA …

Establishment and function of chromatin modification at enhancers

A Tafessu, LA Banaszynski - Open biology, 2020 - royalsocietypublishing.org
How a single genome can give rise to distinct cell types remains a fundamental question in
biology. Mammals are able to specify and maintain hundreds of cell fates by selectively …

Genetic code expansion and dCas9-DAXXHBD as synthetic routes for epigenome editing

M Schrempf - 2020 - diva-portal.org
Epigenome editing has become a promising new tool to study the effects of singular histone
modifications on the transcriptional activity of mammalian cells. Although many different …