The protective role of estrogen and estrogen receptors in cardiovascular disease and the controversial use of estrogen therapy

A Iorga, CM Cunningham, S Moazeni… - Biology of sex …, 2017 - Springer
Epidemiologic studies have previously suggested that premenopausal females have
reduced incidence of cardiovascular disease (CVD) when compared to age-matched males …

[HTML][HTML] Cardiac transmembrane ion channels and action potentials: cellular physiology and arrhythmogenic behavior

V András, J Tomek, N Nagy, L Virág… - Physiological …, 2021 - journals.physiology.org
Cardiac arrhythmias are among the leading causes of mortality. They often arise from
alterations in the electrophysiological properties of cardiac cells and their underlying ionic …

Sex differences in cardiac arrhythmia: a consensus document of the European Heart Rhythm Association, endorsed by the Heart Rhythm Society and Asia Pacific …

C Linde, MG Bongiorni, U Birgersdotter-Green… - Ep …, 2018 - academic.oup.com
There is an increasing awareness that sex is a major determinant of the incidence,
aetiology, and clinical presentation of arrhythmias, and that there are sex differences in …

[HTML][HTML] hERG K+ channels: structure, function, and clinical significance

JI Vandenberg, MD Perry, MJ Perrin… - Physiological …, 2012 - journals.physiology.org
The human ether-a-go-go related gene (hERG) encodes the pore-forming subunit of the
rapid component of the delayed rectifier K+ channel, Kv11. 1, which are expressed in the …

Molecular pathophysiology of congenital long QT syndrome

MS Bohnen, G Peng, SH Robey… - Physiological …, 2017 - journals.physiology.org
Ion channels represent the molecular entities that give rise to the cardiac action potential,
the fundamental cellular electrical event in the heart. The concerted function of these …

Drug-induced proarrhythmia: risk factors and electrophysiological mechanisms

G Frommeyer, L Eckardt - Nature Reviews Cardiology, 2016 - nature.com
Drug-induced ventricular tachyarrhythmias can be caused by cardiovascular drugs,
noncardiovascular drugs, and even nonprescription agents. They can result in arrhythmic …

Contemporary management of arrhythmias during pregnancy

AD Enriquez, KE Economy… - Circulation: Arrhythmia and …, 2014 - Am Heart Assoc
There are few studies on catheter ablation in the pregnant patient. In general, this option
should only be undertaken in a situation where reasonable medical therapy is ineffective …

Mechanisms of sex differences in atrial fibrillation: role of hormones and differences in electrophysiology, structure, function, and remodelling

KE Odening, S Deiß, D Dilling-Boer, M Didenko… - EP …, 2019 - academic.oup.com
Atrial fibrillation (AF) is the clinically most prevalent rhythm disorder with large impact on
quality of life and increased risk for hospitalizations and mortality in both men and women. In …

Atrial fibrillation and ventricular arrhythmias: sex differences in electrophysiology, epidemiology, clinical presentation, and clinical outcomes

AM Gillis - Circulation, 2017 - Am Heart Assoc
Sex-specific differences in the epidemiology, pathophysiology, clinical presentation, clinical
treatment, and clinical outcomes of atrial fibrillation (AF), sustained ventricular arrhythmias …

PhysioZoo: a novel open access platform for heart rate variability analysis of mammalian electrocardiographic data

JA Behar, AA Rosenberg, I Weiser-Bitoun… - Frontiers in …, 2018 - frontiersin.org
Background: The time variation between consecutive heartbeats is commonly referred to as
heart rate variability (HRV). Loss of complexity in HRV has been documented in several …