Distinctive Features of 3‐Acetyl‐and 3‐Benzoyl‐Isocoumarins' Interaction with Active Primary Amines

AS Konovalenko, OV Shablykin… - …, 2023 - Wiley Online Library
Isoquinolones and isoquinolines are crucial natural and synthetic heterocyclic compounds
exhibiting a range of biological activities. A less explored strategy for the recyclization of …

Synthesis and antimicrobial evaluation of novel polyheterocyclic systems derived from cyclopenta[4',5']pyrido[3',2':4,5]furo[3,2-d]pyrimidine

SN Sirakanyan, D Spinelli, A Geronikaki… - Chemistry of …, 2021 - Springer
The synthesis of new cyclopenta [4', 5'] pyrido [3', 2': 4, 5] furo [3, 2-d] pyrimidin-7-amines
have been carried out to study their antimicrobial activity. The biological tests evidenced that …

Synthesis and Antioxidant Activity of N-{[4-(1,3-Benzodioxol-5-yl)tetrahydro-2H-pyran-4-yl]methyl}-Substituted 3-Aryloxy-2-hydroxypropanamines, 2 …

ZS Arustamyan, RE Margaryan, GG Mkryan… - Russian Journal of …, 2024 - Springer
Abstract The alkylation of 2-(1, 3-benzodioxol-5-yl) acetonitrile with bis (2-chloroethyl) ether
gave 4-(1, 3-benzodioxol-5-yl)-tetrahydro-2 H-pyran-4-carbonitrile which was reduced with …

Synthesis and Antiarrhythmic Activity of New Benzodioxol-substituted 4-Spiro [cycloalkane (tetrahydropyran)-6, 7-dimethoxy-1, 2, 3, 4-tetrahydroisoquinolines]

ZS Arustamyan, RE Margaryan, AA Aghekyan… - Russian Journal of …, 2023 - Springer
Abstract The reaction of 1-(3, 4-dimethoxy) phenylcycloalkanemethane-and 4-(3, 4-
dimethoxyphenyl) tetrahydropyran-4-methanamines with benzo [d][1, 3] dioxol-5-carbonyl …

Convenient and versatile method of 8-amino-6-(2-R-thiazol-4-yl)-1, 7-naphthyridines synthesis

A Konovalenko, O Shablykin… - Current Chemistry …, 2024 - m.growingscience.com
On the base of 3-formylpicolinic acid by two successive heterocyclizations (the formation of a
pyrone fragment by the cyclization of chloroacetone with the carboxyl and formyl groups; …

1H-isochromene-1-ones and isoquinoline-1 (2H)-ones with carbonyl group in position 3: Features of synthetic approaches and transformation.

AS Konovalenko, OV Shablykina… - … : Online Journal of …, 2022 - search.ebscohost.com
Oxygen-containing heterocyclic 1H-isochromen-1-ones are core structural components of
various natural products and biologically active compounds. They are used as functional …

[PDF][PDF] The effect of heterocyclic substituent at C-3 position of 1-(4-methyl-piperazin-1-yl) isoquinolines on their anticancer activity

AS Konovalenko, VV Zhirnov, OV Shablykin… - Biopolymers and …, 2022 - researchgate.net
Aim. A comparative analysis of the anti-cancer activity of 1-(4-methylpiperazin-1-yl)
isoquinolines with different heteroaromatic substituents in С-3 position: 2-methylthiazol-4-yl …

Synthesis and Antioxidant Activity (4-(Benzo [d][1, 3]-dioxol-6-yl)-tetrahydro-2H-pyran-4-yl) methylsubstituted Aryloxypropanolamines, Aminoamides and …

ZS Arustamyan, RE Margaryan… - Žurnal …, 2024 - journals.rcsi.science
Abstract Alkylation of 3, 4-methylenedioxyphenylacetоnitrile with 2, 2-dichlorodiethyl ether
gave the corresponding nitrile the reduction of which with lithium aluminum hydride isolated …

Synthesis and antiarrhythmic activity of a new benzodioxolsubstituted 4-spirocycloalkan (tetrahydropyran)-6, 7-dimethoxy-1, 2, 3, 4-tetrahydroisoquinolines

ZS Arustamyan, RE Margaryan… - Žurnal …, 2023 - journals.rcsi.science
Abstract By the reaction of 1-(3, 4-dimethoxy) phenylcycloalkanmethan-and 4-(3, 4-
dimethoxyphenyl) tetrahydropyran-4-methanamines with benzo [d][1, 3] dioxol-5-carbonyl …

[引用][C] Вплив природи гетероциклічного замісника у положенні 3 1-(4-метилпіперазін-1-іл) ізохінолінів на протипухлинну активність

АС Коноваленко, ОВ Шабликін… - Biopolymers …, 2022 - … of Sciences of Ukraine, Institute of …