Over two thousand plant species have been modified morphologically through cultivation
and human use. Here, we review three aspects of crop domestication that are currently …

Telomere maintenance and DNA repair are crucial processes that protect the genome
against instability. RTEL1, an essential iron–sulfur cluster-containing helicase, is a dominant …

Genome packaging by nucleosomes is a hallmark of eukaryotes. Histones and the pathways
that deposit, remove, and read histone modifications are deeply conserved. Yet, we lack …

Orthologs of the yeast telomere protein Stn1 are present in plants, but other components of
the Cdc13/Stn1/Ten1 (CST) complex have only been found in fungi. Here we report the …

Telomeres are highly repetitive DNA sequences found at the ends of chromosomes that
protect the chromosomes from deterioration duringcell division. Here, using whole-genome …

The intimate connection between telomerase regulation and human disease is now well
established. The molecular basis for telomerase regulation is highly complex and entails …

Pot1 (p rotection oft elomeres 1) is a single-stranded telomere binding protein that is
essential for chromosome end protection and telomere length homeostasis. Arabidopsis …

Telomeres comprise the protective caps of natural chromosome ends and function in the
suppression of DNA damage signaling and cellular senescence. Therefore, techniques …

Abstract Chromatin Assembly Factor 1 (CAF1) is a three-subunit H3/H4 histone chaperone
responsible for replication-dependent nucleosome assembly. It is composed of CAC 1-3 in …

Double-strand breaks are a cataclysmic threat to genome integrity. In higher eukaryotes the
predominant recourse is the nonhomologous end-joining (NHEJ) double-strand break repair …