Measuring differential gene expression with RNA-seq: challenges and strategies for data analysis
F Finotello, B Di Camillo - Briefings in functional genomics, 2015 - academic.oup.com
RNA-seq is a methodology for RNA profiling based on next-generation sequencing that
enables to measure and compare gene expression patterns at unprecedented resolution …
enables to measure and compare gene expression patterns at unprecedented resolution …
Diminishing return for increased Mappability with longer sequencing reads: implications of the k-mer distributions in the human genome
Background The amount of non-unique sequence (non-singletons) in a genome directly
affects the difficulty of read alignment to a reference assembly for high throughput …
affects the difficulty of read alignment to a reference assembly for high throughput …
Characterizing regions in the human genome unmappable by next-generation-sequencing at the read length of 1000 bases
W Li, J Freudenberg - Computational biology and chemistry, 2014 - Elsevier
Repetitive and redundant regions of a genome are particularly problematic for mapping
sequencing reads. In the present paper, we compile a list of the unmappable regions in the …
sequencing reads. In the present paper, we compile a list of the unmappable regions in the …
Cognitive diversity in perceptive informatics and affective computing
DF Hsu - 2013 IEEE 12th International Conference on Cognitive …, 2013 - ieeexplore.ieee.org
The advent of sensor technologies and imaging modalities has greatly increased our ability
to map the brain structure and understand its cognitive function. In order for the acquired Big …
to map the brain structure and understand its cognitive function. In order for the acquired Big …
Development and evaluation of software for applied clinical genomics
C Shyr - 2016 - open.library.ubc.ca
High-throughput next-generation DNA sequencing has evolved rapidly over the past 20
years. The Human Genome Project published its first draft of the human genome in 2000 at …
years. The Human Genome Project published its first draft of the human genome in 2000 at …
[PDF][PDF] Developing a bioinformatics framework for proteogenomics
BS Chapman - 2015 - researchportal.murdoch.edu.au
In the last 15 years, since the human genome was first sequenced, genome sequencing and
annotation have continued to improve. However, genome annotation has not kept up with …
annotation have continued to improve. However, genome annotation has not kept up with …
[HTML][HTML] Diminishing return for increased Mappability with longer sequencing reads: implications of the k-mer distributions in the human genome
P Miramontes, J Freudenberg, W Li - 2014 - oa.las.ac.cn
Background The amount of non-unique sequence (non-singletons) in a genome directly
affects the difficulty of read alignment to a reference assembly for high throughput …
affects the difficulty of read alignment to a reference assembly for high throughput …