Naturally occurring antioxidant therapy in Alzheimer's disease

AE Collins, TM Saleh, BE Kalisch - Antioxidants, 2022 - mdpi.com
It is estimated that the prevalence rate of Alzheimer's disease (AD) will double by the year
2040. Although currently available treatments help with symptom management, they do not …

Copper and copper proteins in Parkinson's disease

S Montes, S Rivera-Mancia, A Diaz-Ruiz… - Oxidative medicine …, 2014 - Wiley Online Library
Copper is a transition metal that has been linked to pathological and beneficial effects in
neurodegenerative diseases. In Parkinson's disease, free copper is related to increased …

Multifaceted roles of copper ions in anticancer nanomedicine

S Yang, Y Song, Y Hu, HJ Chen… - Advanced Healthcare …, 2023 - Wiley Online Library
The significantly increased copper level in tumor tissues and serum indicates the close
association of copper ions with tumor development, making copper ions attractive targets in …

Tetracoordinate Fe3+ Activated Li2ZnAO4 (A = Si, Ge) Near-Infrared Luminescent Phosphors

Y Yang, L Shen, J Zhang, S Zhao, Q Pang… - Inorganic …, 2023 - ACS Publications
Fe3+-doped near-infrared (NIR) phosphors have received a lot of interest because they are
nontoxic, inexpensive, and ecologically benign. In this work, Fe3+-activated Li2ZnAO4 (A …

Copper tannic acid-coordinated metal–organic nanosheets for synergistic antimicrobial and antifouling coatings

J Li, J Li, J Wei, X Zhu, S Qiu… - ACS applied materials & …, 2021 - ACS Publications
The copper tannic acid (CuTA) nanosheets with an excellent antibacterial activity were
successfully prepared, which showed fine antibacterial and antifouling performance after …

Copper-induced cell death and the protective role of glutathione: the implication of impaired protein folding rather than oxidative stress

CM Saporito-Magriñá, RN Musacco-Sebio… - Metallomics, 2018 - academic.oup.com
Copper (Cu) is a bioelement essential for a myriad of enzymatic reactions, which when
present in high concentration leads to cytotoxicity. Whereas Cu toxicity is usually assumed to …

Copper homeostasis and cuproptosis in atherosclerosis: metabolism, mechanisms and potential therapeutic strategies

S Yang, Y Li, L Zhou, X Wang, L Liu, M Wu - Cell Death Discovery, 2024 - nature.com
Copper is an essential micronutrient that plays a pivotal role in numerous physiological
processes in virtually all cell types. Nevertheless, the dysregulation of copper homeostasis …

Abnormal copper homeostasis: mechanisms and roles in neurodegeneration

M Manto - Toxics, 2014 - mdpi.com
As a cofactor of proteins and enzymes involved in critical molecular pathways in mammals
and low eukaryotes, copper is a transition metal essential for life. The intra-cellular and extra …

Pathogenesis of Wilson disease

IF Scheiber, R Brůha, P Dušek - Handbook of clinical neurology, 2017 - Elsevier
Wilson disease is an autosomal-recessive disorder originating from a genetic defect in the
copper-transporting ATPase ATP7B that is required for biliary copper secretion and loading …

A study of dose response and organ susceptibility of copper toxicity in a rat model

V Kumar, J Kalita, UK Misra, HK Bora - … of Trace Elements in Medicine and …, 2015 - Elsevier
Copper (Cu) in higher concentration is toxic and results in various organ dysfunction. We
report Cu concentration in liver, brain and kidney in the rat model following chronic exposure …