Mesoporous silica nanoparticles for pulmonary drug delivery

A Garcia-Fernandez, F Sancenon… - Advanced Drug Delivery …, 2021 - Elsevier
Over the last years, respiratory diseases represent a clinical concern, being included among
the leading causes of death in the world due to the lack of effective lung therapies, mainly …

Non-apoptotic cell death-based cancer therapy: Molecular mechanism, pharmacological modulators, and nanomedicine

X Wang, P Hua, C He, M Chen - Acta Pharmaceutica Sinica B, 2022 - Elsevier
As an emerging cancer therapeutic target, non-apoptotic cell death such as ferroptosis,
necroptosis and pyroptosis, etc., has revealed significant potential in cancer treatment for …

[HTML][HTML] Targeting regulated cell death in tumor nanomedicines

Q Zeng, X Ma, Y Song, Q Chen, Q Jiao, L Zhou - Theranostics, 2022 - ncbi.nlm.nih.gov
Nanomedicines hold great potential in anticancer therapy by modulating the biodistribution
of nanomaterials and initiating targeted oxidative stress damage, but they are also limited by …

3-Bromopyruvate-conjugated nanoplatform-induced pro-death autophagy for enhanced photodynamic therapy against hypoxic tumor

Y Deng, P Song, X Chen, Y Huang, L Hong, Q Jin… - ACS nano, 2020 - ACS Publications
Autophagy triggered by reactive oxygen species (ROS) in photodynamic therapy (PDT)
generally exhibits an anti-apoptotic effect to promote cell survival. Herein, an innovative …

Recent advancements in mesoporous silica nanoparticles towards therapeutic applications for cancer

T Li, S Shi, S Goel, X Shen, X Xie, Z Chen, H Zhang… - Acta biomaterialia, 2019 - Elsevier
Recently, drug delivery systems based on nanotechnology have received great attention in
cancer therapeutics and diagnostics since they can not only improve the treatment efficacy …

[HTML][HTML] Autophagy modulated by inorganic nanomaterials

L Guo, N He, Y Zhao, T Liu, Y Deng - Theranostics, 2020 - ncbi.nlm.nih.gov
With the rapid development of nanotechnology, inorganic nanomaterials (NMs) have been
widely applied in modern society. As human exposure to inorganic NMs is inevitable …

[PDF][PDF] A step-by-step multiple stimuli-responsive nanoplatform for enhancing combined chemo-photodynamic therapy

Y Wang, G Wei, X Zhang, F Xu, X Xiong, S Zhou - Adv. Mater, 2017 - researchgate.net
Over the past ten years, polymeric nanoparticles as promising anticancer drug vehicles have
been extensively explored in cancer chemotherapy.[1–5] These nanoparticles are …

Silica based hybrid materials for drug delivery and bioimaging

E Bagheri, L Ansari, K Abnous, SM Taghdisi… - Journal of Controlled …, 2018 - Elsevier
Silica hybrid materials play an important role in improvement of novel progressive functional
nanomaterials. Study in silica hybrid functional materials is supported by growing interest in …

Targeting cancer cell metabolism with mitochondria-immobilized phosphorescent cyclometalated iridium (III) complexes

JJ Cao, CP Tan, MH Chen, N Wu, DY Yao, XG Liu… - Chemical …, 2017 - pubs.rsc.org
Cancer cell metabolism is reprogrammed to sustain the high metabolic demands of cell
proliferation. Recently, emerging studies have shown that mitochondrial metabolism is a …

Future of nanotherapeutics: Targeting the cellular sub-organelles

X Ma, N Gong, L Zhong, J Sun, XJ Liang - Biomaterials, 2016 - Elsevier
Many diseases originate from alterations at nanoscale levels. Precise drug delivery should
be achieved not only at cell level, but also at organelle level to achieve maximum …