Cellular and molecular mechanisms of curcumin in prevention and treatment of disease

SS Patel, A Acharya, RS Ray, R Agrawal… - Critical reviews in …, 2020 - Taylor & Francis
Curcumin is a naturally occurring polyphenolic compound present in rhizome of Curcuma
longa belonging to the family zingiberaceae. Growing experimental evidence revealed that …

A review of therapeutic potentials of turmeric (Curcuma longa) and its active constituent, curcumin, on inflammatory disorders, pain, and their related patents

BM Razavi, M Ghasemzadeh Rahbardar… - Phytotherapy …, 2021 - Wiley Online Library
Turmeric (Curcuma longa) and its constituent, curcumin, have been used for their
therapeutic properties for a long time. Most of the medicinal impacts of turmeric and …

Curcumin and diabetes: a systematic review

D Zhang, M Fu, SH Gao, JL Liu - … ‐Based Complementary and …, 2013 - Wiley Online Library
Turmeric (Curcuma longa), a rhizomatous herbaceous perennial plant of the ginger family,
has been used for the treatment of diabetes in Ayurvedic and traditional Chinese medicine …

Therapeutic potential of curcumin in diabetic complications

N Parsamanesh, M Moossavi, A Bahrami… - Pharmacological …, 2018 - Elsevier
Diabetes mellitus is an extremely prevalent endocrine disease and a major global public
health concern. Diabetic complications, such as retinopathy, nephropathy, neuropathy and …

Diabetic neuropathy and oxidative stress: therapeutic perspectives

A Hosseini, M Abdollahi - Oxidative medicine and cellular …, 2013 - Wiley Online Library
Diabetic neuropathy (DN) is a widespread disabling disorder comprising peripheral
nerves′ damage. DN develops on a background of hyperglycemia and an entangled …

Role of curcumin in the management of pathological pain

J Sun, F Chen, C Braun, YQ Zhou, H Rittner, YK Tian… - Phytomedicine, 2018 - Elsevier
Background: Pathological pain conditions can be triggered after peripheral nerve injury
and/or inflammation. It is a major clinical problem that is poorly treated with available …

[HTML][HTML] Utility of curcumin for the treatment of diabetes mellitus: evidence from preclinical and clinical studies

S Rivera-Mancía, J Trujillo, JP Chaverri - Journal of Nutrition & Intermediary …, 2018 - Elsevier
Turmeric or Curcuma longa is a natural product, whose medicinal properties have been
extensively studied and a wide variety of therapeutic effects on several diseases such as …

Curcumin ameliorated diabetic neuropathy partially by inhibition of NADPH oxidase mediating oxidative stress in the spinal cord

WC Zhao, B Zhang, MJ Liao, WX Zhang, WY He… - Neuroscience …, 2014 - Elsevier
Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases are the main enzymes
that produce oxidative stress, which plays an important role in painful diabetic neuropathy …

Alleviation of cisplatin‐induced hepatotoxicity by gliclazide: Involvement of oxidative stress and caspase‐3 activity

F Taghizadeh, SJ Hosseinimehr… - Pharmacology …, 2021 - Wiley Online Library
Aims Cisplatin (CP), as an effective alkylating agent, is widely used in cancer treatment,
while hepatotoxicity is one of its side effects. Gliclazide (GLZ), as an oral hypoglycemic drug …

Effects of curcumin and its different formulations in preclinical and clinical studies of peripheral neuropathic and postoperative pain: a comprehensive review

P Basu, C Maier, A Basu - International Journal of Molecular Sciences, 2021 - mdpi.com
Lesion or disease of the somatosensory system leads to the development of neuropathic
pain. Peripheral neuropathic pain encompasses damage or injury of the peripheral nervous …