Cytoplasmic dynein 1 is an important microtubule-based motor in many eukaryotic cells.
Dynein has critical roles both in interphase and during cell division. Here, we focus on …

Filamentous fungi constitute a large group of eukaryotic microorganisms that grow by
forming simple tube-like hyphae that are capable of differentiating into more-complex …

Eukaryotic cells create internal order by using protein motors to transport molecules and
organelles along cytoskeletal tracks. Recent genomic and functional studies suggest that …

The multiple functions of lysosomes are critically dependent on their ability to undergo
bidirectional movement along microtubules between the center and the periphery of the cell …

We present an analysis of over 1,100 of the∼ 10,000 predicted proteins encoded by the
genome sequence of the filamentous fungus Neurospora crassa. Seven major areas of …

Filamentous fungi are a large and evolutionarily successful group of organisms of enormous
ecological importance (27, 114). Fungi also have a considerable impact on our economy …

Early in evolution, the diversification of membrane-bound compartments that characterize
eukaryotic cells was accompanied by the elaboration of molecular machineries that mediate …

Filamentous fungi are a large and ancient clade of microorganisms that occupy a broad
range of ecological niches. The success of filamentous fungi is largely due to their elongate …

We describe a versatile strategy for generating gene replacement mutants in the
phytopathogenic fungus Ustilago maydis. The system includes the choice of 32 different …

One kind of the most extremely polarized cells in nature are the indefinitely growing hyphae
of filamentous fungi. A continuous flow of secretion vesicles from the hyphal cell body to the …