[HTML][HTML] The role of m6A-associated membraneless organelles in the RNA metabolism processes and human diseases
F Bu, H Wang, C Xu, K Song, Z Dai, L Wang, J Ying… - Theranostics, 2024 - ncbi.nlm.nih.gov
Abstract N6-methyladenosine (m6A) is the most abundant post-transcriptional dynamic RNA
modification process in eukaryotes, extensively implicated in cellular growth, embryonic …
modification process in eukaryotes, extensively implicated in cellular growth, embryonic …
Cancer Plasticity in Therapy Resistance: Mechanisms and Novel Strategies
X Niu, W Liu, Y Zhang, J Liu, J Zhang, B Li, Y Qiu… - Drug Resistance …, 2024 - Elsevier
Therapy resistance poses a significant obstacle to effective cancer treatment. Recent
insights into cell plasticity as a new paradigm for understanding resistance to treatment: as …
insights into cell plasticity as a new paradigm for understanding resistance to treatment: as …
Inhibition of histone deacetylase activity increases cisplatin efficacy to eliminate metastatic cells in pediatric liver cancers
R Gulati, Y Fleifil, K Jennings, A Bondoc, G Tiao… - Cancers, 2024 - mdpi.com
Simple Summary Patients with pediatric liver cancers hepatoblastoma and hepatocellular
carcinoma very often develop lung metastases. These cancers can present with lung …
carcinoma very often develop lung metastases. These cancers can present with lung …
WTAP/IGF2BP3 mediated m6A modification of the EGR1/PTEN axis regulates the malignant phenotypes of endometrial cancer stem cells
B Wang, Y Wang, W Wang, Z Wang, Y Zhang… - Journal of Experimental …, 2024 - Springer
Endometrial cancer (EC) stem cells (ECSCs) are pivotal in the oncogenesis, metastasis,
immune escape, chemoresistance, and recurrence of EC. However, the specific mechanism …
immune escape, chemoresistance, and recurrence of EC. However, the specific mechanism …
Intricate effects of post-translational modifications in liver cancer: mechanisms to clinical applications
Y Zhang, W Xu, C Peng, S Ren, C Zhang - Journal of Translational …, 2024 - Springer
Liver cancer is a significant global health challenge, with hepatocellular carcinoma (HCC)
being the most prevalent form, characterized by high incidence and mortality rates. Despite …
being the most prevalent form, characterized by high incidence and mortality rates. Despite …
YTHDF3-mediated m6A modification of NKD1 regulates hepatocellular carcinoma invasion and metastasis by activating the WNT/β-catenin signaling axis
S Chen, L Wang, Z Xu, L Chen, Q Li, F Zhong… - Experimental Cell …, 2024 - Elsevier
Abstract N6-methyladenosine (m6A) alteration is an epigenetic regulator widely involved in
the tumorigenicity of hepatocellular carcinoma (HCC). The role of YTH N6-methyladenosine …
the tumorigenicity of hepatocellular carcinoma (HCC). The role of YTH N6-methyladenosine …
Multi-transcriptomics analysis of microvascular invasion-related malignant cells and development of a machine learning-based prognostic model in hepatocellular …
H Huang, F Wu, Y Yu, B Xu, D Chen, Y Huo… - Frontiers in …, 2024 - frontiersin.org
Background Microvascular invasion (MVI) stands as a pivotal pathological hallmark of
hepatocellular carcinoma (HCC), closely linked to unfavorable prognosis, early recurrence …
hepatocellular carcinoma (HCC), closely linked to unfavorable prognosis, early recurrence …
METTL Family in Healthy and Disease
J He, F Hao, S Song, J Zhang, H Zhou, J Zhang… - Molecular Biomedicine, 2024 - Springer
Transcription, RNA splicing, RNA translation, and post-translational protein modification are
fundamental processes of gene expression. Epigenetic modifications, such as DNA …
fundamental processes of gene expression. Epigenetic modifications, such as DNA …
Nucleolar NOL9 regulated by DNA methylation promotes hepatocellular carcinoma growth by activating wnt/beta-catenin pathway
C Xie, X Chen, X Song, B Zhang, Q Lian, L Peng - 2024 - researchsquare.com
Hepatocellular carcinoma (HCC) presents significant clinical challenges, necessitating a
deeper understanding of its molecular drivers for improved therapeutic strategies. Our study …
deeper understanding of its molecular drivers for improved therapeutic strategies. Our study …