Food allergy: a review and update on epidemiology, pathogenesis, diagnosis, prevention, and management

SH Sicherer, HA Sampson - Journal of Allergy and Clinical Immunology, 2018 - Elsevier
This review provides general information to serve as a primer for those embarking on
understanding food allergy and also details advances and updates in epidemiology …

The microbiome in early life: implications for health outcomes

S Tamburini, N Shen, HC Wu, JC Clemente - Nature medicine, 2016 - nature.com
Recent studies have characterized how host genetics, prenatal environment and delivery
mode can shape the newborn microbiome at birth. Following this, postnatal factors, such as …

Healthy infants harbor intestinal bacteria that protect against food allergy

T Feehley, CH Plunkett, R Bao, SM Choi Hong… - Nature medicine, 2019 - nature.com
There has been a striking generational increase in life-threatening food allergies in
Westernized societies,. One hypothesis to explain this rising prevalence is that twenty-first …

Microbiota therapy acts via a regulatory T cell MyD88/RORγt pathway to suppress food allergy

A Abdel-Gadir, E Stephen-Victor, GK Gerber… - Nature medicine, 2019 - nature.com
The role of dysbiosis in food allergy (FA) remains unclear. We found that dysbiotic fecal
microbiota in FA infants evolved compositionally over time and failed to protect against FA in …

Short chain fatty acids prevent high-fat-diet-induced obesity in mice by regulating G protein-coupled receptors and gut microbiota

Y Lu, C Fan, P Li, Y Lu, X Chang, K Qi - Scientific reports, 2016 - nature.com
Elucidating the mechanisms by which short chain fatty acids (SCFA) reduce body weight
may assist in the development of an effective weight control strategy. Dietary …

[HTML][HTML] Dietary fiber and bacterial SCFA enhance oral tolerance and protect against food allergy through diverse cellular pathways

J Tan, C McKenzie, PJ Vuillermin, G Goverse… - Cell reports, 2016 - cell.com
The incidence of food allergies in western countries has increased dramatically in recent
decades. Tolerance to food antigens relies on mucosal CD103+ dendritic cells (DCs), which …

Food allergy

H Renz, KJ Allen, SH Sicherer, HA Sampson… - Nature reviews Disease …, 2018 - nature.com
Food allergies manifest in a variety of clinical conditions within the gastrointestinal tract, skin
and lungs, with the most dramatic and sometimes fatal manifestation being anaphylactic …

Towards a more comprehensive concept for prebiotics

LB Bindels, NM Delzenne, PD Cani… - Nature reviews …, 2015 - nature.com
The essential role of the gut microbiota for health has generated tremendous interest in
modulating its composition and metabolic function. One of these strategies is prebiotics …

Childhood development and the microbiome—the intestinal microbiota in maintenance of health and development of disease during childhood development

V Ronan, R Yeasin, EC Claud - Gastroenterology, 2021 - Elsevier
The composition of the intestinal microbiome affects health from the prenatal period
throughout childhood, and many diseases have been associated with dysbiosis. The gut …

Total fecal microbiota transplantation alleviates high-fat diet-induced steatohepatitis in mice via beneficial regulation of gut microbiota

D Zhou, Q Pan, F Shen, H Cao, W Ding, Y Chen… - Scientific reports, 2017 - nature.com
Non-alcoholic steatohepatitis (NASH) is an epidemic metabolic disease with limited
therapeutic strategies. Cumulative data support the pivotal role of gut microbiota in NASH …