Background Bioactive compounds possess plenty of health benefits, but they are chemically
unstable and susceptible to oxidative degradation. The application of pure bioactive …

Phenolic compounds constitute one of the important classes of secondary metabolites in the
plants. Flavonoids are primary phenolic compounds found in natural drugs. Naringenin is a …

Hydrogel-forming microarray patches (HF-MAPs) are used to circumvent the skin barrier and
facilitate the noninvasive transdermal delivery of many hydrophilic substances. However …

Naringenin (NRG), predominant flavanone in grapefruits, possesses anti-inflammatory, anti-
carcinogenic, hepato-protective and anti-lipid peroxidation effects. Slow dissolution after oral …

Design: Six healthy volunteers received orally 135 mg of each compound, hesperetin and
naringenin, under fasting conditions. Blood samples were collected at 14 different time …

The aim of this review is to draw attention on potential applications of phospholipids in drug
delivery system through different sources, structure, properties and as carrier. Phospholipids …

Herein, we report green synthesized nanoparticles based on stabilization by plant gums,
loaded with citrus fruits flavonoids Hesperidin (HDN) and Naringin (NRG) as novel …

Introduction: In recent years, the number of active pharmaceutical ingredients with high
therapeutic impact, but very low water solubility, has increased significantly. Thus, a great …

Introduction: Amorphous solid dispersions are considered as one of the most powerful
strategies to formulate poorly soluble drugs. They are made up of an active pharmaceutical …

Lyophilized rutin nanocrystals were intensively evaluated regarding their physicochemical
properties with respect to particle size analyses, crystallinity, kinetic solubility and dissolution …