Breast cancer; discovery of novel diagnostic biomarkers, drug resistance, and therapeutic implications

S Afzal, M Hassan, S Ullah, H Abbas… - Frontiers in molecular …, 2022 - frontiersin.org
Breast cancer is the second most reported cancer in women with high mortality causing
millions of cancer-related deaths annually. Early detection of breast cancer intensifies the …

Circular RNAs as potential biomarkers in breast cancer

FDE De Palma, F Salvatore, JG Pol, G Kroemer… - Biomedicines, 2022 - mdpi.com
Due to the high heterogeneity and initially asymptomatic nature of breast cancer (BC), the
management of this disease depends on imaging together with immunohistochemical and …

The analysis of platelet-derived circRNA repertoire as potential diagnostic biomarker for non-small cell lung cancer

S D'ambrosi, A Visser, M Antunes-Ferreira, A Poutsma… - Cancers, 2021 - mdpi.com
Simple Summary Interaction between blood platelets and cancer cells play an important role
in various steps of cancer development and progression. These interactions lead to changes …

[HTML][HTML] Hsa_circ_0092276 promotes doxorubicin resistance in breast cancer cells by regulating autophagy via miR-348/ATG7 axis

Q Wang, D Liang, P Shen, Y Yu, Y Yan, W You - Translational Oncology, 2021 - Elsevier
Previous study has confirmed that hsa_circ_0092276 is highly expressed in doxorubicin
(DOX)-resistant breast cancer cells, indicating that hsa_circ_0092276 may be involved in …

Contents in tumor-educated platelets as the novel biosource for cancer diagnostics

Q Zhang, X Song, X Song - Frontiers in Oncology, 2023 - frontiersin.org
Liquid biopsy, a powerful non-invasive test, has been widely used in cancer diagnosis and
treatment. Platelets, the second most abundant cells in peripheral blood, are becoming one …

Potential impact of Preoperative circulating biomarkers on individual Escalating/de-Escalating strategies in early breast Cancer

C Gianni, M Palleschi, F Merloni, S Bleve, C Casadei… - Cancers, 2022 - mdpi.com
Simple Summary Advancements in molecular technologies have extended the potential role
of circulating biomarkers in diagnosis, disease monitoring, and outcome prediction …

Breast cancer: Circular RNAs mediating efficacy in preclinical in vivo models

UH Weidle, HE Hsia, U Brinkmann - Cancer Genomics & …, 2023 - cgp.iiarjournals.org
In order to identify new targets and treatment modalities for breast cancer, we searched the
literature for circular RNAs (circRNAs) with efficacy in preclinical breast cancer-related in …

The role of m6A‐modified CircEPHB4 in glioma pathogenesis: Insights into cancer stemness metastasis

Y Liao, X Qiu, J Liu, Z Zhang, B Liu… - Annals of Clinical and …, 2023 - Wiley Online Library
Objective While existing literature has provided insights into involvement of circEPHB4,
SOX2 in glioma, their precise molecular mechanisms and synergistic implications in glioma …

Protein-coding circular RNAs–mechanism, detection, and their role in cancer and neurodegenerative diseases

G Lindner, K Takenaka, K Santucci, Y Gao… - Biochemical and …, 2023 - Elsevier
Circular RNAs (circRNAs) are a unique class of non-coding RNAs and were originally
thought to have no protein-coding potential due to their lack of a 5′ cap and 3′ poly (A) …

Small circular interfering RNAs (sciRNAs) as a potent therapeutic platform for gene-silencing

H Jahns, R Degaonkar, P Podbevsek… - Nucleic Acids …, 2021 - academic.oup.com
In order to achieve efficient therapeutic post-transcriptional gene-silencing mediated by the
RNA interference (RNAi) pathway, small interfering RNAs (siRNAs) must be chemically …