Behavioral neuroscience tests such as the Light/Dark Test, the Open Field Test, the Elevated
Plus Maze Test, and the Three Chamber Social Interaction Test have become both essential …

Globally, methamphetamine is one of the most widely used illicit substances. Despite this,
there are no Food and Drug Administration (FDA)-approved pharmacotherapies for treating …

Atrazine is a pesticide used to control weeds in both in pre-and post-emergence crops. The
chronic exposure to atrazine can lead to severe damage in animals, especially in the …

Modernity imposes a toll on the sleep time of young population, with concomitant increase in
symptoms of anxiety and depression. Whether there is a causal relationship between these …

Postpartum depression is a mentally disabling disease with multifactorial etiology that affects
women worldwide. It can also influence child development and lead to behavioral and …

Autism is a neurodevelopmental disorder that is more frequently diagnosed in men.
Nevertheless, through current diagnostic tools, women have also been found to be affected …

Ketamine is an anesthetic drug that also has antidepressant properties, with quick action.
Despite the great number of studies showing its effectiveness as a treatment for major …

In early phases of the drug discovery process, evaluating the off-target pharmacology of a
candidate drug is important when considering potential safety risks. Such off-target liabilities …

Varenicline is an orally administered α4β2 nicotinic acetylcholine (Ach) receptor, partial
agonist. This drug has been known to be more effective in the treatment of nicotine …

A atrazina é um dos herbicidas mais utilizados no Brasil e no mundo. Este praguicida e
seus metabólitos são encontrados em águas superficiais e subterrâneas nas localidades …