It is evident that site-specific systemic drug delivery can reduce side effects, systemic toxicity,
and minimal dosage requirements predominantly by delivering drugs to particular …

The unfolded protein response is a survival signaling pathway that is induced during various
types of ER stress. Here, we determine IRE1's role in miRNA regulation during ER stress …

Background Dengue is a vector-borne debilitating disease that is manifested as mild
dengue fever, dengue with warning signs, and severe dengue. Dengue infection provokes a …

Flaviviruses strategically utilize the endoplasmic reticulum (ER) in their replication cycles.
However, the role of ER autophagy (ER-phagy) in viral replication process remains poorly …

Introduction Fish nucleated red blood cells (RBCs), also known as erythrocytes, play a
crucial role in maintaining immune system balance by modulating protein expression in …

The rapid temperature changes caused by global warming significantly challenge fish
survival by affecting various biological processes. Fish generally mitigate stress through …

Global climate change has a significant impact on fish survival and the aquaculture industry.
Even highly adaptable organisms like Siluriformes fish are susceptible to these effects. This …

Dengue virus (DENV) is an important arthropod-borne viral disease, with four antigenically
and genetically diverse serotypes (DENV-1, DENV-2, DENV-3, and DENV-4). Timely and …

Introduction Varicocele is a dilatation of the internal spermatic vein and it is generally
recognized as one cause of male infertility. This study aimed to analyze the roles of …

Dengue virus (DENV) is the most prevalent arthropod-borne flavivirus and imposes a
significant healthcare threat worldwide. At present no FDA-approved specific antiviral …