Fluorescence-guided surgery is an intraoperative optical imaging method that provides
surgeons with real-time guidance for the delineation of tumours. Currently, in phase 1 and 2 …

Optical imaging has become an indispensable technology in the clinic. The molecular
design of cell-targeted and highly sensitive materials, the validation of specific disease …

In the past several decades, a number of novel fluorescence image-guided surgery (FGS)
contrast agents have been under development, with many in clinical translation and …

Most tumors are easily missed and misdiagnosed due to the lack of specific clinical signs
and symptoms in the early stage. Thus, an accurate, rapid and reliable early tumor detection …

Endoscopy is a clinical gold standard to exam the interior of a hollow organ or body cavity.
For the first of time, this study presents the design and construction of a fluorescent …

Molecular imaging is an emerging strategy for in vivo visualization of cancer over time based
on biological mechanisms of disease activity. Optical imaging methods offer a number of …

Optical endoscopy is the primary diagnostic and therapeutic tool for management of
gastrointestinal (GI) malignancies. Most GI neoplasms arise from precancerous lesions; …

Surgical resection constitutes the first choice of treatment for colorectal cancer (CRC).
Despite advancements in intraoperative navigation, there remains a considerable lack of …

Adenoma miss rates in colonoscopy are unacceptably high, especially for sessile serrated
adenomas/polyps (SSA/Ps) and in high-risk populations, such as patients with Lynch …

Flexible high-definition white-light endoscopy is the current gold standard in screening for
cancer and its precursor lesions in the gastrointestinal tract. However, miss rates are high …