COVID‐19: An Overview of SARS‐CoV‐2 Variants—The Current Vaccines and Drug Development

N Bostanghadiri, P Ziaeefar, MG Mofrad… - BioMed Research …, 2023 - Wiley Online Library
The world is presently in crisis facing an outbreak of a health‐threatening microorganism
known as COVID‐19, responsible for causing uncommon viral pneumonia in humans. The …

Impact of COVID-19 on male fertility

AB Collins, L Zhao, Z Zhu, NT Givens, Q Bai… - Urology, 2022 - Elsevier
COVID-19, the clinical condition caused by the SARS-CoV-2 virus, has been associated with
massive cytokine storm and damage to multiple organ systems. Although evidence for the …

[HTML][HTML] EndoC-βH5 cells are storable and ready-to-use human pancreatic beta cells with physiological insulin secretion

B Blanchi, M Taurand, C Colace, S Thomaidou… - Molecular …, 2023 - Elsevier
Objectives Readily accessible human pancreatic beta cells that are functionally close to
primary adult beta cells are a crucial model to better understand human beta cell physiology …

Review of Janus Kinase Inhibitors as Therapies for Noninfectious Uveitis

HY Juan, SJ Sheu, DK Hwang - Journal of Ocular Pharmacology …, 2024 - liebertpub.com
Uveitis remains one of the leading causes of blindness worldwide, with different etiologies
requiring separate approaches to treatment. For over a decade, oral, topical, and local …

The role of the HIV-1 gut reservoir in driving early cardiovascular events in people living with HIV

K Kramer, A Michael, G Quiñones, S Roa… - Frontiers in Drug …, 2024 - frontiersin.org
People with HIV (PWH), even when well-controlled on antiretroviral therapy (ART), are at an
increased risk for cardiovascular disease (CVD) and CVD events including sudden cardiac …

Development of Diphenyl carbonate-crosslinked cyclodextrin based nanosponges for oral delivery of baricitinib: formulation, characterization and pharmacokinetic …

MF Aldawsari, AH Alhowail, MK Anwer… - International Journal of …, 2023 - Taylor & Francis
Background The aim of the present investigation is to prepare baricitinib (BAR)-loaded
diphenyl carbonate (DPC) β-cyclodextrin (βCD) based nanosponges (NSs) to improve the …

Green electrochemical sensor based on ZnO@ α-Fe2O3 NPs modified carbon paste electrode for sensitive voltammetric determination of the FDA-approved Anti …

MB Ali, AM Abdel-Raoof, S Morshedy, EA Matter… - Sustainable Chemistry …, 2024 - Elsevier
In this study, we developed an electrochemical sensor for the sensitive voltammetric
determination of Baricitinib (BCT), a recently FDA-approved medication for curing COVID …

Therapeutic Response of Alopecia Areata‐Associated Nail Changes to Baricitinib

A Wittmer, K De Jong, L Bolish… - Case Reports in …, 2024 - Wiley Online Library
Nail changes are seen in some individuals with alopecia areata, with the most common
variants including pitting and trachyonychia. The nail findings are presumed to be due to the …

Pharmaceutical aspects of JAK inhibitors: a comparative review

S Jinesh, R Radhakrishnan - Inflammopharmacology, 2024 - Springer
Janus kinase inhibitors (JAKIs) are a new class of drugs used in the treatment of a
heterogeneous group of diseases, mainly inflammatory and autoimmune diseases. Janus …

Foresee novel targets for Alzheimer's disease by investigating repurposed drugs

K Agarwal, DP Katare… - CNS & Neurological …, 2023 - benthamdirect.com
Background: Alzheimer's Disease (AD) is the most rampant neurodegenerative disorder
which has caused havoc worldwide. More than a century has passed since the first case of …