The current paradigm of onset and progression of periodontitis includes oral dysbiosis
directed by inflammophilic bacteria, leading to altered resolution of inflammation and lack of …

Age-related macular degeneration (AMD) remains a major cause of legal blindness, and
treatment for the geographic atrophy form of AMD is a significant unmet need. Dysregulation …

Rheumatoid arthritis (RA) is one of the most frequent inflammatory rheumatic diseases,
having a considerably increased prevalence of mortality and morbidity due to cardiovascular …

Systemic lupus erythematosus is a chronic connective tissue disease associated with an
increased risk of premature atherosclerosis. It is estimated that approximately 10% of SLE …

Cerebral and cardiovascular ischaemic events are frequent complications of SLE and
constitute primary causes of permanent damage. However, the pathogenic determinants of …

Background The complement system plays an important role in pathophysiology of
cardiovascular disease (CVD), and might be involved in accelerated atherogenesis in …

Objective: To review the latest progress on the pathogenic mechanism and management of
rheumatoid arthritis (RA)-associated coronary artery disease (CAD), and propose advice on …

A new monoterpenoid glycoside (1 R, 2 R, 4 S)-1, 8-epoxy-p-menthan-2-O-β-D-
glucopyranosyl-(1→ 4)-β-D-glucopyranoside (1) and a new phenolic glycoside, cis-1-(3 …

Background Coronary artery disease (CAD) is the leading cause of mortality and morbidity
worldwide. Previous studies have shown that complement component 3 (C3) is associated …

Objective Elevated levels of cell-bound complement activation products (CB-CAPs)(C4d
deposition on B lymphocytes (BC4d) and/or erythrocytes (EC4d)) are sensitive and specific …