The effects of mutations on gene expression and alternative splicing
Understanding the relationship between mutations and their genomic and phenotypic
consequences has been a longstanding goal of evolutionary biology. However, few studies …
consequences has been a longstanding goal of evolutionary biology. However, few studies …
The genome-wide rate and spectrum of EMS-induced heritable mutations in the microcrustacean Daphnia: on the prospect of forward genetics
Forward genetic screening using the alkylating mutagen ethyl methanesulfonate (EMS) is an
effective method for identifying phenotypic mutants of interest, which can be further …
effective method for identifying phenotypic mutants of interest, which can be further …
Measuring mutagenicity in ecotoxicology: A case study of Cd exposure in Chironomus riparius
Existing mutagenicity tests for metazoans lack the direct observation of enhanced germline
mutation rates after exposure to anthropogenic substances, therefore being inefficient …
mutation rates after exposure to anthropogenic substances, therefore being inefficient …
What can we infer about mutation calling by using time‐series mutation accumulation data and a Bayesian Mutation Finder?
T Maruki, A Ozere, J Freeman… - Ecology and …, 2024 - Wiley Online Library
Accurate estimates of mutation rates derived from genome‐wide mutation accumulation
(MA) data are fundamental to understanding basic evolutionary processes. The rapidly …
(MA) data are fundamental to understanding basic evolutionary processes. The rapidly …
Accelerated rates of large-scale mutations in the presence of copper and nickel
Mutation rate variation has been under intense investigation for decades. Despite these
efforts, little is known about the extent to which environmental stressors accelerate mutation …
efforts, little is known about the extent to which environmental stressors accelerate mutation …
Spontaneous rate of clonal single nucleotide mutations in Daphnia galeata
Mutations are the ultimate source of heritable variation and therefore the fuel for evolution,
but direct estimates of mutation rates exist only for few species. We estimated the …
but direct estimates of mutation rates exist only for few species. We estimated the …
Fitness effects of spontaneous mutations in a warming world
Spontaneous mutations fuel evolutionary processes and differ in consequence, but the
consequences depend on the environment. Biophysical considerations of protein …
consequences depend on the environment. Biophysical considerations of protein …
Metal exposure causes rDNA copy number to fluctuate in mutation accumulation lines of Daphnia pulex
Ribosomal (r) DNA is a highly dynamic, conserved, multigene family whose sequence
homogeneity is thought to be maintained by intra-and interchromosomal recombination …
homogeneity is thought to be maintained by intra-and interchromosomal recombination …
Spontaneous rate of clonal mutations in Daphnia galeata
Mutations are the ultimate source of heritable variation and therefore the fuel for evolution,
but direct estimates exist only for few species. We estimated the spontaneous nucleotide …
but direct estimates exist only for few species. We estimated the spontaneous nucleotide …
[图书][B] Evolution of Repetitive DNA: Methodologies, Expansions, and Constraints
JM Flynn - 2021 - search.proquest.com
Repetitive DNA is ubiquitous in eukaryotic genomes, but a clear link between its structure,
abundance, and biological significance is lacking. There are two main types of repetitive …
abundance, and biological significance is lacking. There are two main types of repetitive …