Amorphous solid dispersions: An update for preparation, characterization, mechanism on bioavailability, stability, regulatory considerations and marketed products

P Pandi, R Bulusu, N Kommineni, W Khan… - International journal of …, 2020 - Elsevier
Amorphous solid dispersions (ASDs) are being employed frequently to improve
bioavailability of poorly soluble molecules by enhancing the rate and extant of dissolution in …

Overview of the manufacturing methods of solid dispersion technology for improving the solubility of poorly water-soluble drugs and application to anticancer drugs

P Tran, YC Pyo, DH Kim, SE Lee, JK Kim, JS Park - Pharmaceutics, 2019 - mdpi.com
Approximately 40% of new chemical entities (NCEs), including anticancer drugs, have been
reported as poorly water-soluble compounds. Anticancer drugs are classified into biologic …

Inhalable particulate drug delivery systems for lung cancer therapy: Nanoparticles, microparticles, nanocomposites and nanoaggregates

HM Abdelaziz, M Gaber, MM Abd-Elwakil… - Journal of Controlled …, 2018 - Elsevier
There is progressive evolution in the use of inhalable drug delivery systems (DDSs) for lung
cancer therapy. The inhalation route offers many advantages, being non-invasive method of …

Self-assembled amphiphilic zein-lactoferrin micelles for tumor targeted co-delivery of rapamycin and wogonin to breast cancer

SA Sabra, AO Elzoghby, SA Sheweita… - European Journal of …, 2018 - Elsevier
Protein-based micelles have shown significant potential for tumor-targeted delivery of anti-
cancer drugs. In this light, self-assembled nanocarriers based on GRAS (Generally …

Implications of protein-and peptide-based nanoparticles as potential vehicles for anticancer drugs

AO Elzoghby, MM Elgohary, NM Kamel - Advances in protein chemistry …, 2015 - Elsevier
Protein-based nanocarriers have gained considerable attention as colloidal carrier systems
for the delivery of anticancer drugs. Protein nanocarriers possess various advantages …

[PDF][PDF] RETRACTED ARTICLE: Potential of solid dispersions to enhance solubility, bioavailability, and therapeutic efficacy of poorly water-soluble drugs: newer …

S Alshehri, SS Imam, A Hussain, MA Altamimi… - Drug …, 2020 - Taylor & Francis
Abstract We, the Editors and Publisher of Drug Delivery have retracted the following article:
Sultan Alshehri, Syed Sarim Imam, Afzal Hussain, Mohammad A. Altamimi, Nabil K …

Protein-lipid nanohybrids as emerging platforms for drug and gene delivery: challenges and outcomes

M Gaber, W Medhat, M Hany, N Saher, JY Fang… - Journal of Controlled …, 2017 - Elsevier
Nanoparticulate drug delivery systems have been long used to deliver a vast range of drugs
and bioactives owing to their ability to demonstrate novel physical, chemical, and/or …

Lactoferrin-tagged quantum dots-based theranostic nanocapsules for combined COX-2 inhibitor/herbal therapy of breast cancer

AS AbdElhamid, DG Zayed, MW Helmy… - …, 2018 - Taylor & Francis
Aim: Herein, tumor-targeted quantum dots (QDs)-based theranostic nanocapsules (NCs)
coloaded with celecoxib and honokiol were developed. Materials & methodology: The …

Natural polymeric nanoparticles for brain-targeting: implications on drug and gene delivery

AO Elzoghby, MM Abd-Elwakil… - Current …, 2016 - ingentaconnect.com
There is a broad range of biological, chemical and physical hurdles for drugs to reach the
brain. Nanoparticulate drug delivery systems hold tremendous potential for diagnosis and …

Shell-crosslinked zein nanocapsules for oral codelivery of exemestane and resveratrol in breast cancer therapy

AO Elzoghby, SA El-Lakany, MW Helmy… - …, 2017 - Taylor & Francis
Aim: Oral administration of exemestane (EXM) and resveratrol (RES) for breast cancer
therapy has been limited by their poor solubility and low permeability. Methods: In this study …