[HTML][HTML] Unveiling the Therapeutic Potential of Folate-Dependent One-Carbon Metabolism in Cancer and Neurodegeneration

AF Sobral, A Cunha, V Silva, E Gil-Martins… - International Journal of …, 2024 - mdpi.com
Cellular metabolism is crucial for various physiological processes, with folate-dependent
one-carbon (1C) metabolism playing a pivotal role. Folate, a B vitamin, is a key cofactor in …

The association between serum homocysteine and depression: A systematic review and meta‐analysis of observational studies

F Moradi, K Lotfi, M Armin, CCT Clark… - European Journal of …, 2021 - Wiley Online Library
Background Hyperhomocysteinaemia is known to interfere with neurological functions;
however, there is a controversy regarding the relationship between homocysteine and …

Prevalence of malnutrition in patients with Parkinson's disease: a systematic review

KW Kacprzyk, M Milewska, A Zarnowska, M Panczyk… - Nutrients, 2022 - mdpi.com
Objectives: This systematic review analyzed the prevalence of malnutrition in patients with
Parkinson's Disease. Study design: a systematic review. Method: Four databases …

Fractures in Parkinson's disease: injury patterns, hospitalization, and therapeutic aspects

N Mühlenfeld, N Söhling, I Marzi, M Pieper… - European journal of …, 2021 - Springer
Aim The primary aim of this study was to analyze the frequency and characteristic patterns of
fall-related fractures as well as consecutive hospitalization and management relating to such …

Nutritional status associated with molecular biomarkers, physiological indices, and clinical severity in Parkinson's disease patients

TK Lin, YY Chang, NC Chen, CW Liou, MY Lan… - International journal of …, 2020 - mdpi.com
This study is intended to explore the associations between nutritional status and molecular
biomarkers and the clinical severity of Parkinson's disease (PD), as well as to examine the …

Low magnesium in conjunction with high homocysteine increases DNA damage in healthy middle aged Australians

VS Dhillon, P Deo, M Fenech - European Journal of Nutrition, 2024 - Springer
Purpose Magnesium is one of the most common elements in the human body and plays an
important role as a cofactor of enzymes required for DNA replication and repair and many …

Prevalence of malnutrition/malnutrition risk and nutrition-related risk factors among patients with Parkinson's disease: systematic review and meta-analysis

J Fu, Z Li, F Wang, K Yu - Nutritional Neuroscience, 2022 - Taylor & Francis
Introduction The clinical symptoms and nutritional status of patients with Parkinson's disease
(PwP) are interrelated, and the clinical outcomes in malnourished patients are often poor …

Synaptic remodeling and reduced expression of the transcription factors, HES1 and HES5, in the cortex neurons of cognitively impaired hyperhomocysteinemic mice

JW Zhang, YM Ma, L Jing, YL Wang… - Pathology-Research and …, 2020 - Elsevier
Hyperhomocysteinemia (HHcy) is associated with cognitive impairment and
neurodegenerative diseases. The synaptic ultrastructure and the expression of hairy …

[HTML][HTML] Homocysteine aggravates DNA damage by impairing the FA/Brca1 Pathway in NE4C murine neural stem cells

Y Yan, Y Yin, X Feng, Y Chen, J Shi… - … Journal of Medical …, 2020 - ncbi.nlm.nih.gov
There is existing evidence that elevated homocysteine (Hcy) levels are risk factors for some
neurodegenerative disorders. The pathogenesis of neurological diseases could be …

Factors that predict 1-year incident hip and non-hip fractures for home care recipients: a linked-data retrospective cohort study

C McArthur, G Ioannidis, M Jantzi, L Hillier… - Journal of the American …, 2021 - Elsevier
Objectives The purpose of our study was to identify factors that predict 1-year incident hip
and major osteoporotic non-hip fractures (ie, wrist, spine, pelvis, humerus) for home care …