Aspirin and left ventricular assist devices: rationale and design for the international randomized, placebo‐controlled, non‐inferiority ARIES HM3 trial

MR Mehra, DL Crandall, F Gustafsson… - European Journal of …, 2021 - Wiley Online Library
Aims Over decades, left ventricular assist device (LVAD) technology has transitioned from
less durable bulky pumps to smaller continuous‐flow pumps which have substantially …

Mechanical circulatory support devices in advanced heart failure: 2020 and beyond

JL Vieira, HO Ventura, MR Mehra - Progress in Cardiovascular Diseases, 2020 - Elsevier
Substantial progress in the field of mechanical circulatory support (MCS) has expanded the
treatment options for patients with advanced-stage heart failure (HF). Currently available …

A fully magnetically levitated left ventricular assist device

MR Mehra, N Uriel, Y Naka… - … England Journal of …, 2019 - Mass Medical Soc
Background In two interim analyses of this trial, patients with advanced heart failure who
were treated with a fully magnetically levitated centrifugal-flow left ventricular assist device …

Two-year outcomes with a magnetically levitated cardiac pump in heart failure

MR Mehra, DJ Goldstein, N Uriel… - … England Journal of …, 2018 - Mass Medical Soc
Background In an early analysis of this trial, use of a magnetically levitated centrifugal
continuous-flow circulatory pump was found to improve clinical outcomes, as compared with …

[HTML][HTML] A fully magnetically levitated circulatory pump for advanced heart failure

MR Mehra, Y Naka, N Uriel, DJ Goldstein… - New England journal …, 2017 - Mass Medical Soc
Background Continuous-flow left ventricular assist systems increase the rate of survival
among patients with advanced heart failure but are associated with the development of …

Hemocompatibility-related outcomes in the MOMENTUM 3 trial at 6 months: a randomized controlled study of a fully magnetically levitated pump in advanced heart …

N Uriel, PC Colombo, JC Cleveland, JW Long… - Circulation, 2017 - Am Heart Assoc
Background: The HeartMate 3 (HM3) Left Ventricular Assist System (LVAS)(Abbott) is a
centrifugal, fully magnetically levitated, continuous-flow blood pump engineered to enhance …

Evaluation of low-intensity anti-coagulation with a fully magnetically levitated centrifugal-flow circulatory pump—the MAGENTUM 1 study

I Netuka, P Ivák, Z Tučanová, S Gregor… - The Journal of Heart and …, 2018 - Elsevier
Background The HeartMate 3 left ventricular assist system is engineered to avoid pump
thrombosis, yet bleeding complications persist. We investigated the safety of low-intensity …

Fluid dynamics in the HeartMate 3: influence of the artificial pulse feature and residual cardiac pulsation

L Wiegmann, B Thamsen, D De Zélicourt… - Artificial …, 2019 - Wiley Online Library
Ventricular assist devices (VADs), among which the HeartMate 3 (HM3) is the latest clinically
approved representative, are often the therapy of choice for patients with end‐stage heart …

Heartmate 3 fully magnetically levitated left ventricular assist device for the treatment of advanced heart failure–1 year results from the Ce mark trial

T Krabatsch, I Netuka, JD Schmitto, D Zimpfer… - Journal of cardiothoracic …, 2017 - Springer
Abstract Background The HeartMate 3 Left Ventricular Assist System (LVAS)(St. Jude
Medical Inc., St Paul, MN) with full magnetic levitation allows for wide and consistent blood …

The burden of haemocompatibility with left ventricular assist systems: a complex weave

MR Mehra - European heart journal, 2019 - academic.oup.com
Contemporary durable mechanical circulatory support devices, based on axial or centrifugal
continuous blood flow and most aptly referred to as left ventricular assist systems, have …