Ulcerative colitis [UC] is a chronic inflammatory bowel disease [IBD] characterised by colonic
inflammation extending to a variable extent from the rectum. Care of the patient with UC …

Background The Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE)
initiative of the International Organization for the Study of Inflammatory Bowel Diseases …

Ulcerative colitis (UC) is a chronic relapsing and remitting gastrointestinal disorder of
uncertain aetiology. The last two decades have seen an expansion in the therapeutic …

In recent years, the therapeutic goals in ulcerative colitis (UC) have become increasingly
stringent. Histological features seem to be a reliable predictor of disease outcomes after …

The concept of disease clearance has been proposed as a potential target in ulcerative
colitis (UC). We conducted a systematic review to investigate the role of disease clearance …

The main therapeutic goal of ulcerative colitis (UC) is to induce and maintain remission to
prevent long-term disease progression. Treat-to-target strategies, first introduced by the …

Background: Endoscopic and histological activity scores in ulcerative colitis (UC) are
associated with clinical outcomes and have become important targets of clinical trials …

Introduction The STRIDE consensus intends to complement the clinical endpoint with an
endoscopic endpoint of mucosal healing and others as treatment targets in ulcerative colitis …

Objective This systematic literature review (SLR) assessed the effects of endoscopic
mucosal healing and histologic remission on clinical, quality-of-life (QoL), and economic …

Structural repair of the intestinal epithelium is strongly correlated with disease remission in
inflammatory bowel disease (IBD); however, ulcer healing is not addressed by existing …