Nonintercalating DNA-binding ligands: Specificity of the interaction and their use as tools in
biophysical, biochemical and biological investigations of the genetic material - ScienceDirect Skip to …

A family of compounds which appear to bind reversibly to double stranded DNA without
intercalation between DNA base pairs has been defined. Methods are described by which …

Binding of o1igopeptiL; s to nucleic acids has been the subject of numerous studies during
the past few years. These studies were usually undertaken to try to understand the nature …

1. Electrostatic Interactions (a) Determination of the number of electrostatic bonds in protein-
nucleic acid complexes (b) Electrostatic interactions mediated by divalent cations 2 …

There is much interest in the design and synthesis of chemical compounds that possess
binding specificity comparable with that of bacterial repressors. These compounds could be …

The accumulated knowledge about the structure of protein-DNA complexes allowed us to
understand the mechanisms of protein-DNA recognition and searching for a specific site on …

Jacques Ninio addresses molecular biology from the evolutionist's viewpoint, reviewing
major research areas such as acquisitive evolution; the comparison of protein structures in …

Publisher Summary Transfer ribonucleic acid (tRNA) is the term used to describe a group of
low molecular weight RNA molecules that play a vital part in protein synthesis Transfer …

The protomeric form of the cyclic AMP receptor protein (CRP) of Escherichia coli is
composed of two identical subunits of molecular weight 22,500 and contains two buried and …

The specificity of binding interactions between regulatory proteins and DNA is a
consequence of cqmplementarity between the sequences of specific reaction centers on the …