Soil stores more carbon (C) than all vegetation and the atmosphere combined. Soil C stocks
are broadly shaped by temperature, moisture, soil physical characteristics, vegetation, and …

Developing cost-efficient biotechnological processes is a major challenge in replacing fossil-
based industrial production processes. The remarkable progress in genetic engineering …

Species interactions drive evolution while evolution shapes these interactions. The resulting
eco-evolutionary dynamics and their repeatability depend on how adaptive mutations …

The strategy that microbial decomposers take with respect to using substrate for growth
versus maintenance is one essential biological determinant of the propensity of carbon to …

Microbial growth is a clear example of organization and structure arising in nonequilibrium
conditions. Due to the complexity of the microbial metabolic network, elucidating the …

Quantifying the contribution of individual molecular components to complex cellular
processes is a grand challenge in systems biology. Here we establish a general theoretical …

Identifying genetic factors that contribute to the evolution of adaptive phenotypes in
pathogenic bacteria is key to understanding the establishment of infectious diseases. In this …

The fitness landscape is a concept commonly used to describe evolution towards optimal
phenotypes. It can be reduced to mechanistic detail using genome-scale models (GEMs) …

Overflow metabolism is a phenomenon extended in nature, ranging from microbial to cancer
cells. Accumulation of overflow metabolites pose a challenge for large-scale bioprocesses …

Interactive microbial communities are ubiquitous, influencing biogeochemical cycles and
host health. One widespread interaction is nutrient exchange, or cross-feeding, wherein …