Aneurysmal subarachnoid haemorrhage (aSAH) presents a challenge to clinicians because
of its multisystem effects. Advancements in computed tomography (CT), endovascular …

The impact of stroke on global health is profound, with both high mortality and morbidity
rates. This condition can result from cerebral ischemia, intracerebral hemorrhage (ICH), and …

Transforming growth factor-β-activated kinase 1 (TAK1) positively regulates oxidative stress
and inflammation in different diseases. Takinib, a novel and specific TAK1 inhibitor, has …

Regulation of the redox system by branched-chain amino acid transferase 1 (BCAT1) is of
great significance in the occurrence and development of diseases, but the relationship …

Background Early severe cerebral edema and chronic hydrocephalus are the primary cause
of poor prognosis in patients with subarachnoid hemorrhage (SAH). This study investigated …

Aneurysmal subarachnoid hemorrhage is a medical condition that can lead to intracranial
hypertension, negatively impacting patients' outcomes. This review article explores the …

Oxidative stress and neuroinflammation are two major causes leading to early brain injury
after subarachnoid hemorrhage (SAH). Nuclear factor E2-related factor 2 (Nrf2) is a critical …

Background and purpose Subarachnoid hemorrhage (SAH) is a devastating stroke, in which
acidosis is one of detrimental complications. The extracellular pH reduction can activate G …

Background Early brain injury (EBI) refers to a severe brain injury that occurs within hours to
days after subarachnoid hemorrhage (SAH). Neuronal damage in EBI is considered a key …

Subarachnoid hemorrhage is a devastating sequela of aneurysm rupture. Because it
disproportionately affects younger patients, the population impact of hemorrhagic stroke …