Annexins (ANXs) exert different functions in cell biological and pathological processes and
are thus known as double or multi-faceted proteins. These sophisticated proteins might …

The malaria-causing parasite, Plasmodium falciparum completely remodels its host red
blood cell (RBC) through the export of several hundred parasite proteins, including …

The most severe form of malaria, caused by infection with Plasmodium falciparum parasites,
continues to be an important cause of human suffering and poverty. The P. falciparum …

Presentation of the variant antigen, Plasmodium falciparum erythrocyte membrane protein 1
(EMP1), at knob-like protrusions on the surface of infected red blood cells, underpins the …

Apicomplexan parasites that reside within a parasitophorous vacuole harbor a conserved
pore-forming protein that enables small-molecule transfer across the parasitophorous …

During its intraerythrocytic life cycle, the human malaria parasite Plasmodium falciparum
supplements its nutritional requirements by scavenging substrates from the plasma through …

Protein export and host membrane remodeling are crucial for multiple Plasmodium species
to establish a niche in infected hosts. To better understand the contribution of these …

The pathology associated with malaria infection is largely due to the ability of infected
human RBCs to adhere to a number of receptors on endothelial cells within tissues and …

Background There is a clear need for novel approaches to malaria vaccine development.
We aimed to develop a genetically attenuated blood-stage vaccine and test its safety …

Malaria parasites increase their host erythrocyte's permeability to various nutrients, fueling
intracellular pathogen development and replication. The plasmodial surface anion channel …