[HTML][HTML] Ocular complications of diabetes mellitus

N Sayin, N Kara, G Pekel - World journal of diabetes, 2015 - ncbi.nlm.nih.gov
Diabetes mellitus (DM) is a important health problem that induces ernestful complications
and it causes significant morbidity owing to specific microvascular complications such as …

A review of clinical trials of anti-VEGF agents for diabetic retinopathy

BP Nicholson, AP Schachat - Graefe's Archive for Clinical and …, 2010 - Springer
Background Diabetic retinopathy (DR) is a leading cause of vision loss in the working-age
population worldwide. Many observational and preclinical studies have implicated vascular …

Safety and Efficacy of Ranibizumab in Diabetic Macular Edema (RESOLVE Study) A 12-month, randomized, controlled, double-masked, multicenter phase II study

P Massin, F Bandello, JG Garweg, LL Hansen… - Diabetes …, 2010 - Am Diabetes Assoc
OBJECTIVE The expression of vascular endothelial growth factor (VEGF) is elevated in
diabetic macular edema (DME). Ranibizumab binds to and inhibits multiple VEGF variants …

Diabetic macular edema

F Bandello, MB Parodi, P Lanzetta, A Loewenstein… - Macular …, 2017 - karger.com
Diabetic macular edema (DME), defined as a retinal thickening involving or approaching the
center of the macula, represents the most common cause of vision loss in patients affected …

Pathophysiology and treatment of diabetic retinopathy

F Bandello, R Lattanzio, I Zucchiatti, C Del Turco - Acta diabetologica, 2013 - Springer
In the past years, the management of diabetic retinopathy (DR) relied primarily on a good
systemic control of diabetes mellitus, and as soon as the severity of the vascular lesions …

Current treatments in diabetic macular oedema: systematic review and meta-analysis

JA Ford, N Lois, P Royle, C Clar, D Shyangdan… - BMJ open, 2013 - bmjopen.bmj.com
Objectives The aim of this systematic review is to appraise the evidence for the use of anti-
VEGF drugs and steroids in diabetic macular oedema (DMO) as assessed by change in best …

A systematic review of the adverse events of intravitreal anti-vascular endothelial growth factor injections

MI Van der Reis, EC La Heij, Y De Jong-Hesse… - Retina, 2011 - journals.lww.com
Background: Intravitreal ranibizumab and pegaptanib are registered for neovascular age-
related macular degeneration. No formal safety study has been conducted for intravitreal …

[HTML][HTML] Anti-VEGF therapy for diabetic eye diseases

B Bahrami, T Hong, MC Gilles, A Chang - Asia-Pacific journal of …, 2017 - Elsevier
Diabetic retinopathy (DR) is a leading cause of vision impairment and blindness in the
working-age population. The identification of vascular endothelial growth factor (VEGF) as a …

A systematic review and meta-analysis of clinical outcomes of vitrectomy with or without intravitreal bevacizumab pretreatment for severe diabetic retinopathy

LQ Zhao, H Zhu, PQ Zhao, YQ Hu - British journal of ophthalmology, 2011 - bjo.bmj.com
Aims To examine possible benefits of intravitreal bevacizumab (IVB) pretreatment in
vitrectomy for severe diabetic retinopathy. Methods A comprehensive literature search was …

Intraocular pharmacokinetics after a single intravitreal injection of 1.5 mg versus 3.0 mg of bevacizumab in humans

CH Meyer, TU Krohne, FG Holz - Retina, 2011 - journals.lww.com
Purpose: To compare the concentration of unbound bevacizumab in the anterior chamber of
patients with macular edema, who received a single intravitreal injection of two different …