Image-based 3D genomics through chromatin tracing
T Yang, S Wang - Nature Reviews Methods Primers, 2024 - nature.com
Correct organization of higher-order genome folding is essential for the regulation of gene
expression, DNA replication and other genomic functions. Technological advances in high …
expression, DNA replication and other genomic functions. Technological advances in high …
[HTML][HTML] The H3. 3K36M oncohistone disrupts the establishment of epigenetic memory through loss of DNA methylation
Histone H3. 3 is frequently mutated in tumors, with the lysine 36 to methionine mutation
(K36M) being a hallmark of chondroblastomas. While it is known that H3. 3K36M changes …
(K36M) being a hallmark of chondroblastomas. While it is known that H3. 3K36M changes …
[HTML][HTML] PIEZO1-mediated calcium influx transiently alters nuclear mechanical properties via actin remodeling in chondrocytes
JM Garcia-Castorena, R Riester… - Biochemical and …, 2025 - Elsevier
Mechanosensation allows cells to generate intracellular signals in response to mechanical
cues from their environment. Previous research has demonstrated that mechanical stress …
cues from their environment. Previous research has demonstrated that mechanical stress …
Mechanism of EHMT2-mediated genomic imprinting associated with Prader-Willi syndrome
SE Wang, Y Cheng, J Lim, MA Jang… - Research …, 2024 - pmc.ncbi.nlm.nih.gov
Prader-Willi Syndrome (PWS) is caused by loss of expression of paternally expressed genes
in the human 15q11. 2-q13 imprinting domain. A set of imprinted genes that are active on …
in the human 15q11. 2-q13 imprinting domain. A set of imprinted genes that are active on …
Development of a method to tune endogenous gene expression and its application to study dose-sensitivity in transcriptional regulation and random X-chromosome …
G Noviello - 2024 - edoc.hu-berlin.de
Certain biological processes are dose-dependent, depending not only on the presence or
absence of given gene products but also on their specific. The importance of quantitative …
absence of given gene products but also on their specific. The importance of quantitative …