Ferroptosis is a form of regulated cell death characterized by iron-dependent lipid
peroxidation. This process contributes to cellular and tissue damage in various human …

Ferroptosis is a mode of cell death regulated by iron-dependent lipid peroxidation. Growing
evidence suggests ferroptosis induction as a novel anti-cancer modality that could …

Chemotherapy was conventionally applied to kill cancer cells, but regrettably, they also
induce damage to normal cells with high-proliferative capacity resulting in cardiotoxicity …

Relapse is common in remitted patients with major depressive disorder (MDD). Arketamine,
an (R)-enantiomer of ketamine, has persistent prophylactic actions in an inflammatory model …

Vascular calcification, a prevalent pathological alteration in metabolic syndromes, is tightly
related with cardiometabolic risk events. Ferroptosis, a newly iron-dependent programmed …

Rationale: Autophagy dysregulation is known to be a mechanism of doxorubicin (DOX)-
induced cardiotoxicity (DIC). Mitochondrial-Endoplasmic Reticulum Contacts (MERCs) are …

With the progression of tumor treatment, the 5-year survival rate of breast cancer is close to
90%. Cardiovascular toxicity caused by chemotherapy has become a vital factor affecting …

Natural killer (NK) cell-based adoptive immunotherapy has demonstrated encouraging
therapeutic effects in clinical trials for hematological cancers. However, the effectiveness of …

Aims Neoadjuvant chemotherapy (NAC) is the primary preoperative therapy for breast
cancer. The luminal subtype of breast cancer shows less NAC response than the basal …

Cancer immunotherapy has become a mainstream cancer treatment over traditional
therapeutic modes. Cancer cells can undergo programmed cell death including ferroptosis …