Drug development has been a principal driving force in the rapid maturation of the field of
medicinal chemistry during the past several decades. During this period, the intriguing and …

The substitution of primary or secondary alcohols with nucleophiles mediated by a redox
combination of a trialkylor triarylphosphine and a dialkyl azodicarboxylate is popularly …

(S)-as well as (R)-mexiletine [1-(2, 6-dimethylphenoxy)-2-propanamine], a chiral orally
effective antiarrhythmic agent, was prepared by deracemization starting from the …

Methods for synthesizing N-aryl β-amino alcohols and O-aryl β-amino alcohols are
described. The presence of a neighboring hydroxyl or amino group, respectively, is thought …

A new series of 6-substituted 2-aminobenzothiazole derivatives were synthesized and
screened in vitro as potential antimicrobials. Almost all the compounds showed antifungal …

Recent progress in synthetic approaches to the Mitsunobu reaction are reviewed. Efforts that
have focused on the phase‐switching modifications of phosphane, azodicarboxylate, and …

Given the prevalence of aliphatic amines in bioactive small molecules, amine derivatives are
opportune as directing groups. Herein, sulfamides serve as amine surrogates to guide …

We report herein the design of a new visible-light epoxy-based alizarin photosensitizer (AE)
of iodonium salt (Iod) for the cationic polymerization (CP) of epoxidized eugenol monomers …

Oxidative skeletal rearrangement of 5-aryl-4, 5-dihydro-1, 2, 4-oxadiazoles into
quinazolinones is induced by molecular oxygen (under a dry air atmosphere) that likely …

Phthalimide derivatives have been presenting several promising biological activities in the
literature, such as anti-inflammatory, analgesic, antitumor, antimicrobial and anticonvulsant …