Migraine: disease characterisation, biomarkers, and precision medicine

M Ashina, GM Terwindt, MAM Al-Karagholi, I De Boer… - The Lancet, 2021 - thelancet.com
Migraine is a disabling neurological disorder, diagnosis of which is based on clinical criteria.
A shortcoming of these criteria is that they do not fully capture the heterogeneity of migraine …

Structural and functional brain changes in migraine

S Ashina, E Bentivegna, P Martelletti… - Pain and therapy, 2021 - Springer
Migraine is a prevalent primary headache disorder and is usually considered as benign.
However, structural and functional changes in the brain of individuals with migraine have …

Functional magnetic resonance imaging in migraine: A systematic review

S Schramm, C Börner, M Reichert, T Baum… - …, 2023 - journals.sagepub.com
Background Migraine is a highly prevalent primary headache disorder. Despite a high
burden of disease, key disease mechanisms are not entirely understood. Functional …

Functional connectivity studies in migraine: what have we learned?

K Skorobogatykh, WS Van Hoogstraten… - The journal of headache …, 2019 - Springer
Background Resting-state functional connectivity (FC) MRI has widely been used to
understand migraine pathophysiology and to identify an imaging marker of the disorder …

Functional MRI in migraine

R Messina, C Gollion, RH Christensen… - Current Opinion in …, 2022 - journals.lww.com
Summary fMRI studies have captured functional brain changes associated with migraine
phases, leading to an improvement of our understanding of migraine pathophysiology …

Brain functional connectivity in headache disorders: a narrative review of MRI investigations

CD Chong, TJ Schwedt… - Journal of Cerebral Blood …, 2019 - journals.sagepub.com
Resting-state functional magnetic resonance imaging (rs-fMRI) is used to interrogate the
functional connectivity and network organization amongst brain regions. Functional …

Abnormal connectivity within executive resting‐state network in migraine with aura

A Tessitore, A Russo, F Conte… - … : The Journal of …, 2015 - Wiley Online Library
Objective To evaluate the executive control network connectivity integrity in patients with
migraine with aura, in the interictal period, in comparison to patients with migraine without …

Increased intrinsic brain connectivity between pons and somatosensory cortex during attacks of migraine with aura

A Hougaard, FM Amin, HBW Larsson… - Human brain …, 2017 - Wiley Online Library
The neurological disturbances of migraine aura are caused by transient cortical dysfunction
due to waves of spreading depolarization that disrupt neuronal signaling. The effects of …

Reduced functional connectivity between salience and visual networks in migraine with aura

DM Niddam, KL Lai, JL Fuh, CYN Chuang… - …, 2016 - journals.sagepub.com
Background Migraine with visual aura (MA) is associated with distinct visual disturbances
preceding migraine attacks, but shares other visual deficits in between attacks with migraine …

Lack of reproducibility of resting-state functional MRI findings in migraine with aura

A Hougaard, D Gaist, E Garde, P Iversen… - …, 2023 - journals.sagepub.com
Background Several studies have applied resting-state functional MRI to examine whether
functional brain connectivity is altered in migraine with aura patients. These studies had …