[HTML][HTML] Inflammation as a central mechanism in Alzheimer's disease

JW Kinney, SM Bemiller, AS Murtishaw… - Alzheimer's & Dementia …, 2018 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that is characterized
by cognitive decline and the presence of two core pathologies, amyloid β plaques and …

GSK-3 and Tau: a key duet in Alzheimer's disease

CL Sayas, J Ávila - Cells, 2021 - mdpi.com
Glycogen synthase kinase-3 (GSK-3) is a ubiquitously expressed serine/threonine kinase
with a plethora of substrates. As a modulator of several cellular processes, GSK-3 has a …

Extracellular vesicle biomarkers for cognitive impairment in Parkinson's disease

J Blommer, T Pitcher, M Mustapic, E Eren, PJ Yao… - Brain, 2023 - academic.oup.com
Besides motor symptoms, many individuals with Parkinson's disease develop cognitive
impairment perhaps due to coexisting α-synuclein and Alzheimer's disease pathologies and …

Astrocytes in physiological aging and Alzheimer's disease

JJ Rodríguez-Arellano, V Parpura, R Zorec… - Neuroscience, 2016 - Elsevier
Astrocytes are fundamental for homoeostasis, defence and regeneration of the central
nervous system. Loss of astroglial function and astroglial reactivity contributes to the aging of …

Artificial intelligence for Alzheimer's disease: promise or challenge?

C Fabrizio, A Termine, C Caltagirone, G Sancesario - Diagnostics, 2021 - mdpi.com
Decades of experimental and clinical research have contributed to unraveling many
mechanisms in the pathogenesis of Alzheimer's disease (AD), but the puzzle is still …

Stages in the development of Parkinson's disease-related pathology

H Braak, E Ghebremedhin, U Rüb, H Bratzke… - Cell and tissue …, 2004 - Springer
The synucleinopathy, idiopathic Parkinson's disease, is a multisystem disorder that involves
only a few predisposed nerve cell types in specific regions of the human nervous system …

Idiopathic Parkinson's disease: possible routes by which vulnerable neuronal types may be subject to neuroinvasion by an unknown pathogen

H Braak, U Rüb, WP Gai, K Del Tredici - Journal of neural transmission, 2003 - Springer
The progressive, neurodegenerative process underlying idiopathic Parkinson's disease is
associated with the formation of proteinaceous inclusion bodies that involve a few …

The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer's disease

ST Ferreira, WL Klein - Neurobiology of learning and memory, 2011 - Elsevier
Alzheimer's disease (AD) is the 3rd most costly disease and the leading cause of dementia.
It can linger for many years, but ultimately is fatal, the 6th leading cause of death …

The Therapeutic Potential of Rosemary (Rosmarinus officinalis) Diterpenes for Alzheimer's Disease

S Habtemariam - Evidence‐based Complementary and …, 2016 - Wiley Online Library
Rosemary (Rosmarinus officinalis L.) is one of the most economically important species of
the family Lamiaceae. Native to the Mediterranean region, the plant is now widely distributed …

Pathoanatomy of Parkinson's disease

H Braak, E Braak - Journal of neurology, 2000 - Springer
Parkinson's disease is a widespread degenerative illness affecting the human central,
peripheral, and enteric nervous systems. The underlying pathological process progresses …