The rapeseed (Brassica napus L.) are the important oil bearing material worldwide, which
contain wide variety of bioactive components with polyphenolic compounds considered the …

Cardiotoxicity is one of the major safety concerns in the use of drug and is the most common
reason for drug removal from the market. At present, several drugs that have been …

Sinapic acid (SA) is widely used in cosmetics, foods, and pharmaceuticals due to its
antioxidant, anti-inflammatory, neuroprotective, antimicrobial, antifungal, anticancer, and …

Sinapic acid (SA) is a natural pharmacological active compound found in berries, nuts, and
cereals. The current study aimed to investigate the protective effects of SA against …

Methotrexate (MTX; 4‐amino‐10‐methylfolic acid) is a folic acid reductase inhibitor used to
treat autoimmune diseases and certain types of cancer. Testicular toxicity resulting from MTX …

Tobacco smoking is the leading cause of preventable death. Numerous reports link smoking
in pregnancy with serious adverse outcomes, such as miscarriage, stillbirth, prematurity, low …

Among digestive system cancers, the extremely poor prognosis of pancreatic cancer (PC) is
a pressing concern. Nonoperative treatments such as targeted and immunotherapy, have …

Alcoholic liver disease (ALD) is one of the main causes of death in chronic liver disease.
Oxidative stress and pyroptosis are important factors leading to ALD. Bromodomain …

Puerarin (Pue) has been widely used in the treatment of hypertension and cardiovascular
diseases, but the basic mechanism of Pue on myocardial remodeling (MR) of hypertension …

OBJECTIVE: Drug and substance abuse remains a major medical problem globally. Alcohol
consumption, particularly heavy drinking, is an important risk factor for many health …