Peptide and protein nanoparticle conjugates: versatile platforms for biomedical applications

CD Spicer, C Jumeaux, B Gupta… - Chemical Society …, 2018 - pubs.rsc.org
Peptide–and protein–nanoparticle conjugates have emerged as powerful tools for
biomedical applications, enabling the treatment, diagnosis, and prevention of disease. In …

Lipid-based nanoparticles as pharmaceutical drug carriers: from concepts to clinic

A Puri, K Loomis, B Smith, JH Lee… - Critical Reviews™ in …, 2009 - dl.begellhouse.com
In recent years, various nanotechnology platforms in the area of medical biology, including
both diagnostics and therapy, have gained remarkable attention. Moreover, research and …

Barriers to drug delivery in solid tumors

SK Sriraman, B Aryasomayajula, VP Torchilin - Tissue barriers, 2014 - Taylor & Francis
Over the last decade, significant progress has been made in the field of drug delivery. The
advent of engineered nanoparticles has allowed us to circumvent the initial limitations to …

Passive and active drug targeting: drug delivery to tumors as an example

VP Torchilin - Drug delivery, 2010 - Springer
The paradigm of using nanoparticulate pharmaceutical carriers has been well established
over the past decade, both in pharmaceutical research and in the clinical setting. Drug …

Improvement of drug safety by the use of lipid-based nanocarriers

SB Lim, A Banerjee, H Önyüksel - Journal of controlled release, 2012 - Elsevier
Drug toxicity is an important factor that contributes significantly to adverse drug events in
current healthcare practice. Application of lipid-based nanocarriers in drug formulation is …

Liposomal doxorubicin in the treatment of breast cancer patients: a review

J Lao, J Madani, T Puértolas, M Álvarez… - Journal of drug …, 2013 - Wiley Online Library
Drug delivery systems can provide enhanced efficacy and/or reduced toxicity for anticancer
agents. Liposome drug delivery systems are able to modify the pharmacokinetics and …

Polymer micelles with cross-linked polyanion core for delivery of a cationic drug doxorubicin

JO Kim, AV Kabanov, TK Bronich - Journal of Controlled Release, 2009 - Elsevier
Polymer micelles with cross-linked ionic cores were prepared by using block ionomer
complexes of poly (ethylene oxide)-b-poly (methacrylic acid)(PEO-b-PMA) copolymer and …

Antibody-targeted nanoparticles for cancer therapy

F Fay, CJ Scott - Immunotherapy, 2011 - Taylor & Francis
In recent years, nanoparticulate-mediated drug delivery research has examined a full
spectrum of nanoparticles that can be used in diagnostic and therapeutic cancer …

Antibody-modified liposomes for cancer chemotherapy

V Torchilin - Expert opinion on drug delivery, 2008 - Taylor & Francis
Background: Liposomes, phospholipids, nanosized bubbles with a bilayered membrane
structure, have drawn a lot of interest as pharmaceutical carriers for drugs and genes. In …

Antibody-targeted biodegradable nanoparticles for cancer therapy

VH Shargh, H Hondermarck, M Liang - Nanomedicine, 2016 - Taylor & Francis
The use of nanotechnology has great potentials to revolutionize the future cancer diagnosis
and therapy. In this context, various nanoparticles (NPs) have been developed for targeted …