Polarized proteins in endothelium and their contribution to function

AG Wolpe, CA Ruddiman, PJ Hall… - Journal of vascular …, 2021 - karger.com
Protein localization in endothelial cells is tightly regulated to create distinct signaling
domains within their tight spatial restrictions including luminal membranes, abluminal …

Multiscale model of integrin adhesion assembly

TC Bidone, AV Skeeters, PW Oakes… - PLOS Computational …, 2019 - journals.plos.org
The ability of adherent cells to form adhesions is critical to numerous phases of their
physiology. The assembly of adhesions is mediated by several types of integrins. These …

Indacaterol inhibits collective cell migration and IGDQ-mediated single cell migration in metastatic breast cancer MDA-MB-231 cells

S Ayama-Canden, R Tondo, ML Pineros Leyton… - Cell Communication and …, 2023 - Springer
Metastasis is the main cause of deaths related to breast cancer. This is particular the case
for triple negative breast cancer. No targeted therapies are reported as efficient until now …

A flexible loop in the paxillin LIM3 domain mediates its direct binding to integrin β subunits

T Baade, M Michaelis, A Prestel, C Paone, N Klishin… - Plos …, 2024 - journals.plos.org
Integrins are fundamental for cell adhesion and the formation of focal adhesions (FA).
Accordingly, these receptors guide embryonic development, tissue maintenance, and …

A Programmable Toolkit to Dynamically Signal Cells Using Peptide Strand Displacement

KD Riker, ML Daly, MJ Papanikolas… - … Applied Materials & …, 2021 - ACS Publications
The native extracellular matrix communicates and interacts with cells by dynamically
displaying signals to control their behavior. Mimicking this dynamic environment in vitro is …