Microcystin biosynthesis and toxic effects
C Zhou, H Chen, H Zhao, Q Wang - Algal Research, 2021 - Elsevier
Population growth and its associated pressure on agricultural, urban, and industrial
development have increased the incidence of harmful algal blooms. Microcystins are toxins …
development have increased the incidence of harmful algal blooms. Microcystins are toxins …
Through the looking glass: chiral recognition of substrates and products at the active sites of racemases and epimerases
SL Bearne - Chemistry–A European Journal, 2020 - Wiley Online Library
Unlike most enzymes, which exhibit stereospecific substrate binding, racemases and
epimerases bind and catalyze the reversible interconversion of enantiomeric and epimeric …
epimerases bind and catalyze the reversible interconversion of enantiomeric and epimeric …
Unveiling an indole alkaloid diketopiperazine biosynthetic pathway that features a unique stereoisomerase and multifunctional methyltransferase
G Deletti, SD Green, C Weber, KN Patterson… - Nature …, 2023 - nature.com
Abstract The 2, 5-diketopiperazines are a prominent class of bioactive molecules. The
nocardioazines are actinomycete natural products that feature a pyrroloindoline …
nocardioazines are actinomycete natural products that feature a pyrroloindoline …
Feedback Regulation between Aquatic Microorganisms and the Bloom-Forming Cyanobacterium Microcystis aeruginosa
The frequency and intensity of cyanobacterial blooms are increasing worldwide. Interactions
between toxic cyanobacteria and aquatic microorganisms need to be critically evaluated to …
between toxic cyanobacteria and aquatic microorganisms need to be critically evaluated to …
Synthesis of a Truncated Microcystin Tetrapeptide Molecule from a Partial Mcy Gene Cluster in Microcystis Cultures and Blooms
Microcystis spp. threaten freshwater ecosystems through the proliferation of cyanobacterial
harmful algal blooms (cyanoHABs) and production of the hepatotoxin, microcystin. While …
harmful algal blooms (cyanoHABs) and production of the hepatotoxin, microcystin. While …
[HTML][HTML] Identification of a homoarginine biosynthetic gene from a microcystin biosynthetic pathway in Fischerella sp. PCC 9339
Microcystins (MCs) are a family of chemically diverse toxins produced by numerous distantly
related cyanobacteria. They are potent inhibitors of eukaryotic protein phosphatases 1 and …
related cyanobacteria. They are potent inhibitors of eukaryotic protein phosphatases 1 and …
Racemases and epimerases operating through a 1, 1-proton transfer mechanism: reactivity, mechanism and inhibition
MD Lloyd, M Yevglevskis, A Nathubhai… - Chemical Society …, 2021 - pubs.rsc.org
Racemases and epimerases catalyse changes in the stereochemical configurations of chiral
centres and are of interest as model enzymes and as biotechnological tools. They also …
centres and are of interest as model enzymes and as biotechnological tools. They also …
Design and evaluation of substrate–product analog inhibitors for racemases and epimerases utilizing a 1, 1-proton transfer mechanism
SL Bearne - Methods in Enzymology, 2023 - Elsevier
Racemases and epimerases catalyze the inversion of stereochemistry at asymmetric carbon
atoms to generate stereoisomers that often play important roles in normal and pathological …
atoms to generate stereoisomers that often play important roles in normal and pathological …