The human fungal pathogen Cryptococcus neoformans is characterized by its ability to
induce a distinct polysaccharide capsule in response to a number of host-specific …

Fusarium graminearum is an important pathogen of small grains and maize in many areas of
the world. To better understand the molecular mechanisms of F. graminearum pathogenesis …

Fungal microorganisms, including the human pathogenic yeast and filamentous fungi, are
able to synthesize all proteinogenic amino acids, including nine that are essential for …

The interaction of Candida albicans with the innate immune system is the key determinant of
the pathogen/commensal balance and has selected for adaptations that facilitate the …

Cryptococcus neoformans has become a common central nervous system pathogen as the
immunocompromised populations enlarge world-wide. This encapsulated yeast has …

In recent years, incidences of invasive fungal infections have greatly increased, especially in
immunosuppressed patients, but most today's antifungal drugs are not completely effective …

Fungal sulfur uptake is required for incorporation into the sidechains of the amino acids
cysteine and methionine, and is also essential for the biosynthesis of the antioxidant …

Fungal infections are a growing threat to human health. Despite their clinical relevance,
there is a surprisingly limited availability of clinically approved antifungal agents, which is …

Methionine is a sulfur amino acid standing at the crossroads of several biosynthetic
pathways. In fungi, the last step of methionine biosynthesis is catalyzed by a cobalamine …

The ability of the fungal pathogen Cryptococcus neoformans to evade the mammalian innate
immune response and cause disease is partially due to its ability to respond to and survive …