Paracellular permeability and tight junction regulation in gut health and disease
Epithelial tight junctions define the paracellular permeability of the intestinal barrier.
Molecules can cross the tight junctions via two distinct size-selective and charge-selective …
Molecules can cross the tight junctions via two distinct size-selective and charge-selective …
Gut barrier disruption and chronic disease
The intestinal barrier protects the host against gut microbes, food antigens, and toxins
present in the gastrointestinal tract. However, gut barrier integrity can be affected by intrinsic …
present in the gastrointestinal tract. However, gut barrier integrity can be affected by intrinsic …
[HTML][HTML] Serotonin reduction in post-acute sequelae of viral infection
AC Wong, AS Devason, IC Umana, TO Cox… - Cell, 2023 - cell.com
Post-acute sequelae of COVID-19 (PASC," Long COVID") pose a significant global health
challenge. The pathophysiology is unknown, and no effective treatments have been found to …
challenge. The pathophysiology is unknown, and no effective treatments have been found to …
Gut microbiota in COVID-19: key microbial changes, potential mechanisms and clinical applications
The gastrointestinal tract is involved in coronavirus disease 2019 (COVID-19) caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The gut microbiota has …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The gut microbiota has …
Gut microbiome dysbiosis in antibiotic-treated COVID-19 patients is associated with microbial translocation and bacteremia
Although microbial populations in the gut microbiome are associated with COVID-19
severity, a causal impact on patient health has not been established. Here we provide …
severity, a causal impact on patient health has not been established. Here we provide …
Multisystem inflammatory syndrome in children and long COVID: the SARS-CoV-2 viral superantigen hypothesis
Multisystem inflammatory syndrome in children (MIS-C) is a febrile pediatric inflammatory
disease that may develop weeks after initial SARS-CoV-2 infection or exposure. MIS-C …
disease that may develop weeks after initial SARS-CoV-2 infection or exposure. MIS-C …
An open label, non-randomized study assessing a prebiotic fiber intervention in a small cohort of Parkinson's disease participants
DA Hall, RM Voigt, TM Cantu-Jungles… - Nature …, 2023 - nature.com
A pro-inflammatory intestinal microbiome is characteristic of Parkinson's disease (PD).
Prebiotic fibers change the microbiome and this study sought to understand the utility of …
Prebiotic fibers change the microbiome and this study sought to understand the utility of …
Distinct systemic and mucosal immune responses during acute SARS-CoV-2 infection
Coordinated local mucosal and systemic immune responses following severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection either protect against …
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection either protect against …
Gut microbiome alterations in COVID-19
T Zuo, X Wu, W Wen, P Lan - Genomics, Proteomics and …, 2021 - academic.oup.com
Since the outset of the coronavirus disease 2019 (COVID-19) pandemic, the gut microbiome
in COVID-19 has garnered substantial interest, given its significant roles in human health …
in COVID-19 has garnered substantial interest, given its significant roles in human health …
Innate metabolic responses against viral infections
CS Palmer - Nature Metabolism, 2022 - nature.com
Metabolic adaptation to viral infections critically determines the course and manifestations of
disease. At the systemic level, a significant feature of viral infection and inflammation that …
disease. At the systemic level, a significant feature of viral infection and inflammation that …