Target population These recommendations apply to adult patients diagnosed with newly
diagnosed glioblastoma. Question 1 In adult patients (aged 65 and under) with newly …

Background Glioblastoma is an aggressive form of brain cancer. Approximately five in 100
people with glioblastoma survive for five years past diagnosis. Glioblastomas that have a …

Abstract Treatment for glioblastoma (GBM) includes surgical resection and adjuvant
radiotherapy (RT) and chemotherapy. The optimal time interval between surgery and RT …

Recent studies suggested that postoperative hypoxia might trigger invasive tumor growth,
resulting in diffuse/multifocal recurrence patterns. Aim of this study was to analyze distinct …

Background and purpose To evaluate the effect of timing of radiotherapy (RT) on survival in
patients with newly diagnosed primary glioblastoma (GBM) treated with the same …

Background We previously reported the unexpected finding of significantly improved
survival for newly diagnosed glioblastoma in patients when radiation therapy (RT) was …

Introduction For about 30 years, researchers developed prognostic scores and searched for
prognostic factors to predict outcomes for cancer patients. The “Combs Prognostic Score” for …

Background To assess the influence of the time interval between surgical resection and
standard combined chemoradiotherapy on survival in newly diagnosed and homogeneously …

Background Radiation therapy (RT) remains a critical component of multimodality treatment
for medulloblastoma. Traditionally, clinicians strive to start RT within 4–5 weeks of surgery …

Molecular markers define the diagnosis of glioblastoma in the new WHO classification of
2016, challenging neuro-oncology centers to provide timely treatment initiation. The aim of …