An update on African trypanocide pharmaceutics and resistance

KI Kasozi, ET MacLeod, I Ntulume… - Frontiers in Veterinary …, 2022 - frontiersin.org
African trypanosomiasis is associated with Trypanosoma evansi, T. vivax, T. congolense,
and T. brucei pathogens in African animal trypanosomiasis (AAT) while T. b gambiense and …

Predicted impact of COVID-19 on neglected tropical disease programs and the opportunity for innovation

J Toor, ER Adams, M Aliee, B Amoah… - Clinical Infectious …, 2021 - academic.oup.com
Due to the COVID-19 pandemic, many key neglected tropical disease (NTD) activities have
been postponed. This hindrance comes at a time when the NTDs are progressing towards …

The elimination of human African trypanosomiasis: Achievements in relation to WHO road map targets for 2020

JR Franco, G Cecchi, M Paone, A Diarra… - PLoS neglected …, 2022 - journals.plos.org
Background In the 20th century, epidemics of human African trypanosomiasis (HAT)
ravaged communities in a number of African countries. The latest surge in disease …

Monitoring the elimination of human African trypanosomiasis at continental and country level: Update to 2018

JR Franco, G Cecchi, G Priotto, M Paone… - PLoS neglected …, 2020 - journals.plos.org
Background In 2012 human African trypanosomiasis (HAT), also known as sleeping
sickness, was targeted for elimination as a public health problem, set to be achieved by …

Do cryptic reservoirs threaten gambiense-sleeping sickness elimination?

P Büscher, JM Bart, M Boelaert, B Bucheton… - Trends in …, 2018 - cell.com
Trypanosoma brucei gambiense causes human African trypanosomiasis (HAT). Between
1990 and 2015, almost 440000 cases were reported. Large-scale screening of populations …

Modelling for policy: the five principles of the Neglected Tropical Diseases Modelling Consortium

MR Behrend, MG Basáñez, JID Hamley… - PLoS neglected …, 2020 - journals.plos.org
The neglected tropical diseases (NTDs) thrive mainly among the poorest populations of the
world. The World Health Organization (WHO) has set ambitious targets for eliminating much …

Trypa-NO! contributes to the elimination of gambiense human African trypanosomiasis by combining tsetse control with “screen, diagnose and treat” using innovative …

JM Ndung'u, A Boulangé, A Picado… - PLoS neglected …, 2020 - journals.plos.org
Gambiense human African trypanosomiasis (g-HAT) is the chronic form of sleeping sickness
caused by Trypanosoma brucei gambiense in West and Central Africa, while Trypanosoma …

Impact of a small-scale tsetse fly control operation with deltamethrin impregnated “Tiny Targets” on tsetse density and trypanosomes' circulation in the Campo sleeping …

TT Melachio Tanekou… - PLOS Neglected …, 2023 - journals.plos.org
Background Significant progress has been made towards African sleeping sickness
elimination in the last decade. Indeed, the World Health Organization (WHO) global goal of …

The elimination of human African trypanosomiasis is in sight: Report from the third WHO stakeholders meeting on elimination of gambiense human African …

MP Barrett - PLoS neglected tropical diseases, 2018 - journals.plos.org
In 2012, the World Health Organisation (WHO) set out a roadmap for the control, elimination,
or eradication of 17 neglected tropical diseases by 2020 [1]. Many were skeptical about the …

Impact of tiny targets on Glossina fuscipes quanzensis, the primary vector of human African trypanosomiasis in the Democratic Republic of the Congo

I Tirados, A Hope, R Selby, F Mpembele… - PLoS neglected …, 2020 - journals.plos.org
Over the past 20 years there has been a> 95% reduction in the number of Gambian Human
African trypanosomiasis (g-HAT) cases reported globally, largely as a result of large-scale …