Glial roles in sterile inflammation after ischemic stroke

R Koyama, T Shichita - Neuroscience Research, 2023 - Elsevier
Stroke is a leading cause of death and disability worldwide, but there are a limited number of
therapies that improve patients' functional recovery. The complicated mechanisms of post …

Neuroprotection of stem cells against ischemic brain injury: from bench to clinic

X Liu, X Jia - Translational Stroke Research, 2024 - Springer
Neurological injuries can have numerous debilitating effects on functional status including
sensorimotor deficits, cognitive impairment, and behavioral symptoms. Despite the disease …

[HTML][HTML] Click chemistry extracellular vesicle/peptide/chemokine nanocarriers for treating central nervous system injuries

H Ruan, Y Li, C Wang, Y Jiang, Y Han, Y Li… - … Pharmaceutica Sinica B, 2023 - Elsevier
Central nervous system (CNS) injuries, including stroke, traumatic brain injury, and spinal
cord injury, are essential causes of death and long-term disability and are difficult to cure …

Effects of adjuvant berberine therapy on acute ischemic stroke: A meta‐analysis

D Luo, B Yu, S Sun, B Chen, HV Harkare… - Phytotherapy …, 2023 - Wiley Online Library
We conducted a meta‐analysis to evaluate the clinical efficacy of berberine (BBR) in treating
acute ischemic stroke (AIS), explore its anti‐inflammatory effects, and assess its potential …

CD133+ endothelial-like stem cells restore neovascularization and promote longevity in progeroid and naturally aged mice

S Sun, Y Meng, M Li, X Tang, W Hu, W Wu, G Li… - Nature Aging, 2023 - nature.com
The stem cell theory of aging dictates that a decline in the number and/or function of stem
cells causes tissue degeneration and aging; however, it still lacks unequivocal experimental …

[HTML][HTML] M2 microglia-derived extracellular vesicles promote white matter repair and functional recovery via miR-23a-5p after cerebral ischemia in mice

Y Li, Z Liu, Y Song, J Pan, Y Jiang, X Shi, C Liu… - Theranostics, 2022 - ncbi.nlm.nih.gov
Rationale: White matter repair is critical for the cognitive and neurological functional
recovery after ischemic stroke. M2 microglia are well-documented to enhance remyelination …

[HTML][HTML] Flavonoids and ischemic stroke-induced neuroinflammation: focus on the glial cells

W Lu, Z Chen, J Wen - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Ischemic stroke is one of the most cases worldwide, with high rate of morbidity and mortality.
In the pathological process of ischemic stroke, neuroinflammation is an essential process …

Transplantation of endothelial progenitor cells: Summary and prospect

F Yan, J Li, W Zhang - Acta Histochemica, 2023 - Elsevier
Abstract Endothelial Progenitor Cells (EPCs) are precursor cells of endothelial cells (ECs),
which can differentiate into vascular ECs, protect from endothelial dysfunction and tissue …

Activation of astroglial CB1R mediates cerebral ischemic tolerance induced by electroacupuncture

C Yang, J Liu, J Wang, A Yin, Z Jiang… - Journal of Cerebral …, 2021 - journals.sagepub.com
There are no effective treatments for stroke. The activation of endogenous protective
mechanisms is a promising therapeutic approach, which evokes the intrinsic ability of the …

[HTML][HTML] Targeted mitigation of neointimal hyperplasia via magnetic field-directed localization of superparamagnetic iron oxide nanoparticle-labeled endothelial …

Z Li, Y Zhang, M Ma, W Wang, H Hui, J Tian… - Biomedicine & …, 2024 - Elsevier
Background The transplantation of endothelial progenitor cells (EPCs) has been shown to
reduce neointimal hyperplasia following arterial injury. However, the efficacy of this …