The mammalian brain is a complex organ comprising neurons, glia, and more than 1× 1014
synapses. Neurons are a heterogeneous group of electrically active cells, which form the …

Astrocytes comprise half of the cells in the central nervous system and play a critical role in
maintaining metabolic homeostasis. Metabolic dysfunction in astrocytes has been indicated …

Spatial cognition is used by most organisms to navigate their environment. Some species
rely particularly heavily on specialized spatial cognition to survive, suggesting that a …

Neurons migrate from their birthplaces to the destinations, and extending axons navigate to
their synaptic targets by sensing various extracellular cues in spatiotemporally controlled …

HIV infection of astrocytes leads to restricted gene expression and replication but abundant
expression of HIV early genes Tat, Nef and Rev. A great deal of neuroHIV research has so …

Abstract Information exchange between neurons and astrocytes mediated by extracellular
vesicles (EVs) is known to play a key role in the pathogenesis of central nervous system …

Subarachnoid hemorrhage (SAH) significantly compromises the blood-brain barrier (BBB)
and impairs patient recovery. This study elucidates the critical role of astrocytic Neogenin-1 …

Background Glutamate metabolism disorder is an important mechanism of sepsis-
associated encephalopathy (SAE). Astrocytes regulate glutamate metabolism. In septic …

Protein lactylation is a new form of protein post-translational modification that has been
proposed recently. Lactoyl groups are mainly converted from the glycolytic product lactate …

Astrocytes provide trophic and metabolic support to neurons and modulate circuit formation
during development. In addition, astrocytes help maintain neuronal homeostasis through …