Metastable alpha‐rich and beta‐rich conformations of small Aβ42 peptide oligomers

PH Nguyen, F Sterpone… - … : Structure, Function, and …, 2023 - Wiley Online Library
Probing the structures of amyloid‐β (Aβ) peptides in the early steps of aggregation is
extremely difficult experimentally and computationally. Yet, this knowledge is extremely …

Exposure to the electric field: A potential way to block the aggregation of histidine tautomeric isomers of β-amyloid

A Salimi, S Chatterjee, JY Lee - International Journal of Biological …, 2023 - Elsevier
Controlling protein misfolding and accumulation in neurodegeneration is a challenge in
chemical neuroscience. The application of appropriate electric fields (EFs) can be a …

Histidine tautomerism-mediated transthyretin amyloidogenesis: A molecular insight

S Chatterjee, A Salimi, JY Lee - Archives of Biochemistry and Biophysics, 2023 - Elsevier
Abstract Characterization of the conformational alterations involved in monomer misfolding
is essential for elucidating the molecular basis of the initial stage of protein accumulation …