Metabolomics as a tool to investigate HIV/TB co-infection
The HIV/AIDS (human immunodeficiency virus/acquired immunodeficiency syndrome) and
tuberculosis (TB) pandemics are perpetuated by a significant global burden of HIV/TB co …
tuberculosis (TB) pandemics are perpetuated by a significant global burden of HIV/TB co …
Intravenous Bacille Calmette–Guérin vaccination protects simian immunodeficiency virus-infected macaques from tuberculosis
EC Larson, AL Ellis-Connell, MA Rodgers… - Nature …, 2023 - nature.com
Tuberculosis, caused by Mycobacterium tuberculosis (Mtb), is the most common cause of
death in people living with human immunodeficiency virus (HIV). Intra-dermal Bacille …
death in people living with human immunodeficiency virus (HIV). Intra-dermal Bacille …
HIV and the tuberculosis “set point”: how HIV impairs alveolar macrophage responses to tuberculosis and sets the stage for progressive disease
SC Auld, BS Staitieh - Retrovirology, 2020 - Springer
As HIV has fueled a global resurgence of tuberculosis over the last several decades, there is
a growing awareness that HIV-mediated impairments in both innate and adaptive immunity …
a growing awareness that HIV-mediated impairments in both innate and adaptive immunity …
Characteristics of TB/HIV co-infection and patterns of multidrug-resistance tuberculosis in the Northwest Amhara, Ethiopia
A Seid, Y Girma, A Abebe, E Dereb… - Infection and Drug …, 2023 - Taylor & Francis
Background Multidrug-resistant tuberculosis (MDR-TB) has continued to be a serious public
health threat and significantly challenges global TB control and prevention efforts, where the …
health threat and significantly challenges global TB control and prevention efforts, where the …
[HTML][HTML] Discovery of 3H-pyrrolo [2, 3-c] quinolines with activity against Mycobacterium tuberculosis by allosteric inhibition of the glutamate-5-kinase enzyme
M Panciera, E Lence, A Rodriguez, B Gracia… - European Journal of …, 2022 - Elsevier
The therapeutic potential of 3H-pyrrolo [2, 3-c] quinolines—the main core of Marinoquinoline
natural products—has been explored for the development of new anti-TB agents. The …
natural products—has been explored for the development of new anti-TB agents. The …
HIV-Differentiated Metabolite N-Acetyl-L-Alanine Dysregulates Human Natural Killer Cell Responses to Mycobacterium tuberculosis Infection
B Yang, T Mukherjee, R Radhakrishnan… - International Journal of …, 2023 - mdpi.com
Mycobacterium tuberculosis (Mtb) has latently infected over two billion people worldwide
(LTBI) and caused~ 1.6 million deaths in 2021. Human immunodeficiency virus (HIV) co …
(LTBI) and caused~ 1.6 million deaths in 2021. Human immunodeficiency virus (HIV) co …
Tuberculosis-associated immune reconstitution inflammatory syndrome—an extempore game of misfiring with defense arsenals
The lethal combination involving TB and HIV, known as “syndemic” diseases, synergistically
act upon one another to magnify the disease burden. Individuals on anti-retroviral therapy …
act upon one another to magnify the disease burden. Individuals on anti-retroviral therapy …
[HTML][HTML] Vaccination with intravenous BCG protects macaques with pre-existing SIV infection from tuberculosis
EC Larson, AL Ellis-Connell, MA Rodgers… - Research …, 2023 - ncbi.nlm.nih.gov
Tuberculosis (TB) is the most common cause of death in people living with HIV. BCG
delivered intradermally (ID) is the only licensed vaccine to prevent TB. However, it offers little …
delivered intradermally (ID) is the only licensed vaccine to prevent TB. However, it offers little …
Mycobacterium tuberculosis-induced monocyte transcriptional responses associated with resistance to tuberculin skin test/interferon-γ release assay conversion in …
H Hong, KA Dill-Mcfarland, B Benson, JD Simmons… - AIDS, 2023 - journals.lww.com
Objective: To determine whether Mycobacterium tuberculosis (Mtb)-induced monocyte
transcriptional responses differ in people with HIV (PWH) who do (RSTR) or do not (LTBI) …
transcriptional responses differ in people with HIV (PWH) who do (RSTR) or do not (LTBI) …
Higher sensitivity of Xpert MTB/RIF Ultra over Tuberculosis Culture for the diagnosis of spinal tuberculosis with Open or computed tomography–guided biopsies
Background Diagnostic specimens for spinal tuberculosis (STB) are mostly collected via
open surgery. Percutaneous computed tomography (CT)–guided biopsies are used in times …
open surgery. Percutaneous computed tomography (CT)–guided biopsies are used in times …