The role of the gut microbiota in the relationship between diet and human health

BK Perler, ES Friedman, GD Wu - Annual review of physiology, 2023 - annualreviews.org
The interplay between diet, the gut microbiome, and host health is complex. Diets
associated with health have many similarities: high fiber, unsaturated fatty acids, and …

Clinical application of intermittent fasting for weight loss: progress and future directions

KA Varady, S Cienfuegos, M Ezpeleta… - Nature Reviews …, 2022 - nature.com
Intermittent fasting diets have become very popular in the past few years, as they can
produce clinically significant weight loss. These diets can be defined, in the simplest of …

Intermittent fasting and metabolic health

I Vasim, CN Majeed, MD DeBoer - Nutrients, 2022 - mdpi.com
Given the ongoing strain that the obesity epidemic has placed on public health outcomes,
new and effective approaches to weight control are needed. One approach to improving …

[HTML][HTML] Effects of 4-and 6-h time-restricted feeding on weight and cardiometabolic health: a randomized controlled trial in adults with obesity

S Cienfuegos, K Gabel, F Kalam, M Ezpeleta… - Cell metabolism, 2020 - cell.com
Time-restricted feeding (TRF) regimens have grown in popularity; however, very few studies
have examined their weight-loss efficacy. We conducted the first human trial (Clinicaltrials …

Intermittent fasting in the prevention and treatment of cancer

KK Clifton, CX Ma, L Fontana… - CA: a cancer journal for …, 2021 - Wiley Online Library
Chronic caloric restriction (CR) has powerful anticarcinogenic actions in both preclinical and
clinical studies but may be difficult to sustain. As an alternative to CR, there has been …

Cardiometabolic benefits of intermittent fasting

KA Varady, S Cienfuegos, M Ezpeleta… - Annual review of …, 2021 - annualreviews.org
This review aims to summarize the effects of intermittent fasting on markers of
cardiometabolic health in humans. All forms of fasting reviewed here—alternate-day fasting …

Intermittent fasting plus early time-restricted eating versus calorie restriction and standard care in adults at risk of type 2 diabetes: a randomized controlled trial

XT Teong, K Liu, AD Vincent, J Bensalem, B Liu… - Nature Medicine, 2023 - nature.com
Intermittent fasting appears an equivalent alternative to calorie restriction (CR) to improve
health in humans. However, few trials have considered applying meal timing during the …

Effects of intermittent fasting on health, aging, and disease

R De Cabo, MP Mattson - New England Journal of Medicine, 2019 - Mass Medical Soc
Effects of Intermittent Fasting on Health and Aging Evidence is accumulating that eating in a
6-hour period and fasting for 18 hours can trigger a metabolic switch from glucose-based to …

[HTML][HTML] Early time-restricted feeding improves insulin sensitivity, blood pressure, and oxidative stress even without weight loss in men with prediabetes

EF Sutton, R Beyl, KS Early, WT Cefalu, E Ravussin… - Cell metabolism, 2018 - cell.com
Intermittent fasting (IF) improves cardiometabolic health; however, it is unknown whether
these effects are due solely to weight loss. We conducted the first supervised controlled …

Intermittent and periodic fasting, longevity and disease

VD Longo, M Di Tano, MP Mattson, N Guidi - Nature aging, 2021 - nature.com
Intermittent and periodic fasting (IF and PF, respectively) are emerging as safe strategies to
affect longevity and healthspan by acting on cellular aging and disease risk factors, while …