Cataract, a clouding of the lens, is the most common cause of blindness in the world. It has a
marked impact on the wellbeing and productivity of individuals and has a major economic …

The mesenchymal stem cell (MSC) is being broadly studied in clinical trials. Contrary to the
early paradigm of cell replacement and differentiation as a therapeutic mechanism of action …

Complex barriers separate immune-privileged tissues from the circulation. Here, we propose
that cell entry to immune-privileged sites through barriers composed of tight junction …

Most higher animals require sight for survival, yet even minor distortions of the visual axis
can cause blindness. For this reason, intraocular inflammation is incompatible with good …

Posterior Capsule Opacification (PCO) is the most common complication of cataract surgery.
At present the only means of treating cataract is by surgical intervention, and this initially …

Age related macular degeneration (AMD) is a complex multifactorial disease caused by the
interplay of age and genetic and environmental risk factors. A common feature observed in …

It has been over 60 years since the phrase immune privilege was used by Sir Peter
Medawar to describe the lack of an immune response against allografts placed into the …

purpose. To study the role of TGF-β2 in posterior capsule opacification (PCO) and to
determine whether CAT-152 (lerdelimumab), a fully human monoclonal antibody that …

Posterior capsule opacification (PCO) is the most common complication of cataract surgery.
At present the only means of treating cataract is by surgical intervention, and this initially …

purpose. To examine the normal murine corneal stroma for the presence of bone marrow-
derived leukocytes. methods. Wholemounts of paraformaldehyde-fixed corneal stroma from …