Advances and perspectives in carrier-free nanodrugs for cancer chemo-monotherapy and combination therapy

L Huang, S Zhao, F Fang, T Xu, M Lan, J Zhang - Biomaterials, 2021 - Elsevier
Nanocarrier-based drug delivery systems hold impressive promise for biomedical
application because of their excellent water dispersibility, prolonged blood circulation time …

[HTML][HTML] The smart drug delivery system and its clinical potential

D Liu, F Yang, F Xiong, N Gu - Theranostics, 2016 - ncbi.nlm.nih.gov
With the unprecedented progresses of biomedical nanotechnology during the past few
decades, conventional drug delivery systems (DDSs) have been involved into smart DDSs …

A metal–polyphenol‐coordinated nanomedicine for synergistic cascade cancer chemotherapy and chemodynamic therapy

Z Ren, S Sun, R Sun, G Cui, L Hong, B Rao… - Advanced …, 2020 - Wiley Online Library
The clinical application of chemotherapy is impeded by the unsatisfactory efficacy and
severe side effects. Chemodynamic therapy (CDT) has emerged as an efficient strategy for …

An NIR Discrete Metallacycle constructed from Perylene Bisimide and Tetraphenylethylene Fluorophores for imaging‐guided cancer Radio‐chemotherapy

Y Ding, Z Tong, L Jin, B Ye, J Zhou, Z Sun… - Advanced …, 2022 - Wiley Online Library
To promote the clinical theranostic performances of platinum‐based anticancer drugs,
imaging capability is urgently desired, and their chemotherapeutic efficacy needs to be …

Binary cooperative prodrug nanoparticles improve immunotherapy by synergistically modulating immune tumor microenvironment

B Feng, F Zhou, B Hou, D Wang, T Wang… - Advanced …, 2018 - Wiley Online Library
Checkpoint blockade immunotherapy is promising for clinical treatment of various malignant
tumors. However, checkpoint blockade immunotherapy suffers from a low response rate due …

Charge-Convertible Carbon Dots for Imaging-Guided Drug Delivery with Enhanced in Vivo Cancer Therapeutic Efficiency

T Feng, X Ai, G An, P Yang, Y Zhao - ACS nano, 2016 - ACS Publications
Carbon dots (CDs) are remarkable nanocarriers due to their promising optical and
biocompatible capabilities. However, their practical applicability in cancer therapeutics is …

Sequentially responsive shell‐stacked nanoparticles for deep penetration into solid tumors

J Chen, J Ding, Y Wang, J Cheng, S Ji… - Advanced …, 2017 - Wiley Online Library
Nanomedicine to overcome both systemic and tumor tissue barriers ideally should have a
transformable size and surface, maintaining a certain size and negative surface charge for …

Fluorescent carbon quantum dots with intrinsic nucleolus-targeting capability for nucleolus imaging and enhanced cytosolic and nuclear drug delivery

XW Hua, YW Bao, FG Wu - ACS applied materials & interfaces, 2018 - ACS Publications
Nucleolus tracking and nucleus-targeted photodynamic therapy are attracting increasing
attention due to the importance of nucleolus and the sensitivity of nucleus to various …

[HTML][HTML] Light-activated hypoxia-responsive nanocarriers for enhanced anticancer therapy

C Qian, J Yu, Y Chen, Q Hu, X Xiao, W Sun… - … (Deerfield Beach, Fla …, 2016 - ncbi.nlm.nih.gov
A light-activated hypoxia-responsive conjugated polymer-based nanocarrier is developed
for efficiently producing singlet oxygen (1O2) and inducing hypoxia to promote release of its …

Injectable bioresponsive gel depot for enhanced immune checkpoint blockade

S Yu, C Wang, J Yu, J Wang, Y Lu, Y Zhang… - Advanced …, 2018 - Wiley Online Library
Although cancer immunotherapy based on immune checkpoint inhibitors holds great
promise toward many types of cancers, several challenges still remain, associated with low …